Results 11 to 20 of about 464 (154)

Gene- and pathway-level analyses of iCOGS variants highlight novel signaling pathways underlying familial breast cancer susceptibility. [PDF]

Int J Cancer, 2021
Abstract Single‐nucleotide polymorphisms (SNPs) in over 180 loci have been associated with breast cancer (BC) through genome‐wide association studies involving mostly unselected population‐based case‐control series. Some of them modify BC risk of women carrying a BRCA1 or BRCA2 (BRCA1/2) mutation and may also explain BC risk variability in BC‐prone ...
Lonjou C, Eon-Marchais S, Truong T, Dondon MG, Karimi M, Jiao Y, Damiola F, Barjhoux L, Le Gal D, Beauvallet J, Mebirouk N, Cavaciuti E, Chiesa J, Floquet A, Audebert-Bellanger S, Giraud S, Frebourg T, Limacher JM, Gladieff L, Mortemousque I, Dreyfus H, Lejeune-Dumoulin S, Lasset C, Venat-Bouvet L, Bignon YJ, Pujol P, Maugard CM, Luporsi E, Bonadona V, Noguès C, Berthet P, Delnatte C, Gesta P, Lortholary A, Faivre L, Buecher B, Caron O, Gauthier-Villars M, Coupier I, Mazoyer S, Monraz LC, Kondratova M, Kuperstein I, Guénel P, Barillot E, Stoppa-Lyonnet D, Andrieu N, Lesueur F.   +47 more
europepmc   +2 more sources

Familial breast cancer and DNA repair genes: Insights into known and novel susceptibility genes from the GENESIS study, and implications for multigene panel testing. [PDF]

Int J Cancer, 2019
Pathogenic variants in BRCA1 and BRCA2 only explain the underlying genetic cause of about 10% of hereditary breast and ovarian cancer families. Because of cost‐effectiveness, multigene panel testing is often performed even if the clinical utility of testing most of the genes remains questionable.
Girard E, Eon-Marchais S, Olaso R, Renault AL, Damiola F, Dondon MG, Barjhoux L, Goidin D, Meyer V, Le Gal D, Beauvallet J, Mebirouk N, Lonjou C, Coignard J, Marcou M, Cavaciuti E, Baulard C, Bihoreau MT, Cohen-Haguenauer O, Leroux D, Penet C, Fert-Ferrer S, Colas C, Frebourg T, Eisinger F, Adenis C, Fajac A, Gladieff L, Tinat J, Floquet A, Chiesa J, Giraud S, Mortemousque I, Soubrier F, Audebert-Bellanger S, Limacher JM, Lasset C, Lejeune-Dumoulin S, Dreyfus H, Bignon YJ, Longy M, Pujol P, Venat-Bouvet L, Bonadona V, Berthet P, Luporsi E, Maugard CM, Noguès C, Delnatte C, Fricker JP, Gesta P, Faivre L, Lortholary A, Buecher B, Caron O, Gauthier-Villars M, Coupier I, Servant N, Boland A, Mazoyer S, Deleuze JF, Stoppa-Lyonnet D, Andrieu N, Lesueur F.   +63 more
europepmc   +2 more sources

Low life: William Hogarth, visual culture and sociologies of art

The British Journal of Sociology, Volume 72, Issue 4, Page 909-929, September 2021., 2021
Abstract This paper is an effort to understand Hogarth's unique position in early eighteenth century London, so as to grasp the rich complexity of his work. It begins by tracing two rival competing positions in the sociology of art, derived from Becker and Bourdieu, before taking a closer look at how Hogarth's work conjures up a new vision of the world,
Eamonn Carrabine
wiley   +1 more source

Effi Briest and the work on genre

Orbis Litterarum, Volume 75, Issue 4, Page 173-183, August 2020., 2020
Abstract Ever since Erich Auerbach’s harsh verdict in Mimesis, the German realist novel has been seen as a peripheral phenomenon in the history of nineteenth‐century literature. Criticized for being too idealizing, insular, or simply irrelevant, it has gone down in literary history as a less modern form of realism, not being able to join the realist ...
Fredrik Wilhelm Renard
wiley   +1 more source

Adapter l’ironie flaubertienne : l’exemple de Gemma Bovery de Posy Simmonds [PDF]

Synergies Espagne, 2021
Gustave Flaubert a refusé d’illustrer ses livres tout au long de sa vie ; une attitude qui contraste, paradoxalement, avec les nombreuses occasions où ses œuvres ont été adaptées aux formats graphiques et cinématographiques.
Marina Isabel Caballero Muñoz
doaj  

Lire le pastiche

Lingue e Linguaggi, 2012
ENA pastiche of Proust, The Lemoine Affair by Gustave Flaubert, is here considered under a semio-linguistic perspective, which is doomed to locate the marks of a diffuse intertextuality, similar to a playground where the vagaries of sense perception are ...
A. Calì
doaj   +1 more source

A Historical Vignette “Be proud of yourself: you have a History!” ENT illuminated by literature. Gustave Flaubert and the glory of Gensoul

B-ENT, 2007
ENT illuminated by literature. Gustave Flaubert and the glory of Gensoul. Doctor Joseph Gensoul (1797- 1858) has at least two claims to fame as an ENT physician: he was the first to practise the total resection of the superior maxillary bone, and he ...
J. Tainmont
doaj   +2 more sources

Em busca de Emma Bovary

Literatura e Sociedade, 1999
O ensaio empreende uma reflexão sobre as relações entre o Bovarismo, tomando como tema literário, e a forma do Romance, baseada na análise de uma cena central do romance Madame Bovary, de Gustave Flaubert.
Andrea Saad Hossne
doaj   +1 more source

Teorias da criação literária

Semina: Ciências Sociais e Humanas, 2011
O ensaio aborda concepções teóricas em Platão, Edgar Allan Poe, Gustave Flaubert e Jorge Luis Borges, e discute os modos como o pensamento clássico e a modernidade entendem a criação da obra literária.
Luiz Antonio de Figueiredo
doaj   +1 more source

Machado com Flaubert e a escrita anti-bêtise

Revista Criação & Crítica, 2011
The texts “O imortal”, by Machado de Assis, and “La légende de Saint Julien l’Hospitalier”, by Gustave Flaubert, are studied here taking into consideration the ironic play of their writings which make the cliché’s list a narrative strategy common to both
Lívia Cristina Gomes
doaj   +3 more sources