Results 121 to 130 of about 2,218,966 (387)
Gut Symptoms, Gut Dysbiosis and Gut-Derived Toxins in ALS
Many pathogenetic mechanisms have been proposed for amyotrophic lateral sclerosis (ALS). Recently, there have been emerging suggestions of a possible role for the gut microbiota. Gut microbiota have a range of functions and could influence ALS by several mechanisms. Here, we review the possible role of gut-derived neurotoxins/excitotoxins.
Lee, Aven+3 more
openaire +2 more sources
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block+8 more
wiley +1 more source
Investigating the pharmacology is key to the modernization of Chinese Medicine (CM) formulas. However, identifying which are the active compound(s) of CM formulas, which biological entities they target, and through which signaling pathway(s) they act to ...
Tao Huang+10 more
doaj +1 more source
Laboratory investigation of daily food intake and gut evacuation in larvae of African catfish Clarias gariepinus under different feeding conditions [PDF]
Temporary accumulation of ascorbic acid 2-sulfate (AAS) was measured to estimate food intake and gut evacuation in larvae of African catfish. Fish larvae were fed decapsulated cysts of Artemia containing AAS.
García-Ortega, A.+5 more
core +3 more sources
Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova+5 more
wiley +1 more source
The Superpartner Spectrum of Gaugino Mediation [PDF]
We compute the superpartner masses in a class of models with gaugino mediation (or no-scale) boundary conditions at a scale between the GUT and Planck scales.
A.B. Lahanas+36 more
core +2 more sources
Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia+20 more
wiley +1 more source
Nucleon Decay in GUT and Non-GUT SUSY Models [PDF]
I first emphasize the importance of searching for nucleon decay in the context of supersymmetric models. The status of minimal SUSY SU(5) model is reviewed, which can be definitively ruled out by a combination of superKamiokande and LEP-2 experiments ...
Murayama, Hitoshi
core +1 more source
The gauge coupling unification is one of main motivations in the split-SUSY scenario, and the existence of the grand unified theories (GUTs) is assumed.
Haba, Naoyuki, Okada, Nobuchika
core +1 more source
The Reach of the Fermilab Tevatron and CERN LHC for Gaugino Mediated SUSY Breaking Models [PDF]
In supersymmetric models with gaugino mediated SUSY breaking (inoMSB), it is assumed that SUSY breaking on a hidden brane is communicated to the visible brane via gauge superfields which propagate in the bulk.
A. Chamseddine+53 more
core +2 more sources