Results 121 to 130 of about 2,005,973 (405)
PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. [PDF]
, 2019 Chronic gut inflammatory diseases are associated with disruption of intestinal epithelial barriers and impaired mucosal immunity. HIV-1 (HIV) causes depletion of mucosal CD4+ T cells early in infection and disruption of gut epithelium, resulting in ...
Arredondo, Juan +13 more
core
Gutted programs and children's guts [PDF]
Canadian Medical Association Journal, 2008 In polite parlance, it could be said educational administrators have now seen the error of their ways. After gutting physical education programs in the nation's schools a decade ago, they're now madly scrambling to revitalize previously robust physical education programs in the face of a ...
openaire +2 more sources
Beyond the gut bacterial microbiota: The gut virome [PDF]
Journal of Medical Virology, 2016 The gastrointestinal tract is colonized with a highly different population of bacterial, viral, ad fungal species; viruses are reported to be dominant. The composition of gut virome is closely related to dietary habits and surrounding environment. Host and their intestinal microbes live in a dynamic equilibrium and viruses stimulate a low degree of ...
Columpsi, P +7 more
openaire +4 more sources
A new approach to gauge coupling unification and proton decay [PDF]
, 2019 An analytical formalism, including RG running at two loop order, is used to link the supersymmetric and GUT spectra in any GUT model in which the three gauge couplings unify. In each specific GUT model, one can then fully explore the interplay between the pattern of supersymmetry breaking and the prediction for the proton lifetime.
arxiv +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Revista Colombiana de GastroenterologíaIntroducción: en este artículo de revisión se desarrollan los principios básicos para el uso y los mecanismos de acción de los neuromoduladores utilizados en la práctica clínica y su papel en el tratamiento de los diferentes trastornos de la interacción
Luis Fernando Pineda Ovalle +4 more
doaj +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Scientific Reports, 2023 Patients with spinal cord injury (SCI) suffer from major bowel dysfunction, whose exact pathophysiology, particularly the involvement of the enteric nervous system or epithelial dysfunction is poorly understood.
Chloë Lefèvre +9 more
doaj +1 more source
Evolution of Mammals and Their Gut Microbes
Science, 2008 Mammals are metagenomic in that they are composed of not only their own gene complements but also those of all of their associated microbes. To understand the coevolution of the mammals and their indigenous microbial communities, we conducted a network ...
R. Ley +11 more
semanticscholar +1 more source
Supersymmetry Searches in GUT Models with Non-Universal Scalar Masses [PDF]
, 2015 We study SO(10), SU(5) and flipped SU(5) GUT models with non-universal soft supersymmetry-breaking scalar masses, exploring how they are constrained by LHC supersymmetry searches and cold dark matter experiments, and how they can be probed and ...
Cannoni, M. +4 more
core +2 more sources