Results 341 to 350 of about 2,005,973 (405)

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

Cross-feeding-based rational design of a probiotic combination of <i>Bacterides xylanisolvens</i> and <i>Clostridium butyricum</i> therapy for metabolic diseases. [PDF]

Gut Microbes
Qiao S, Wang T, Sun J, Han J, Dai H, Du M, Yang L, Guo CJ, Liu C, Liu SJ, Liu H.   +10 more
europepmc   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Advanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng, Ruizeng Luo, Ying Chen, Xiaoqiang Liu, Yuanyin Xi, Muhammad Usman, Xupin Jiang, Zhou Li, Jiaping Zhang   +8 more
wiley   +1 more source

Gut Microbiota and Their Metabolites: The Hidden Driver of Diabetic Nephropathy? Unveiling Gut Microbe's Role in DN. [PDF]

J Diabetes
Liu J, Guo M, Yuan X, Fan X, Wang J, Jiao X.   +5 more
europepmc   +1 more source

Large‐Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain

Advanced Science, EarlyView.
This study delineates both common and site‐specific proteins linked to various chronic pain conditions, elucidating their implications across molecular pathways and health status. These findings, particularly those proteins with genetic causal links to pain or predictive capabilities, have the potential to significantly benefit both research and ...
Ze‐Yu Li, Qing Ma, Jie Zhang, Rui‐Ying Yin, Jia You, Qi‐Zheng Hao, Xin‐Rui Wu, Ju‐Jiao Kang, Lin‐Bo Wang, Yue‐Ting Deng, Yu‐Zhu Li, Chun Shen, Bang‐Sheng Wu, Jian‐Feng Feng, Yi‐Heng Tu, Xiao Xiao, Jin‐Tai Yu, Wei Cheng   +17 more
wiley   +1 more source

The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T Cells

Advanced Science, EarlyView.
RARα is highly expressed by differentiated effector and exhausted T cells and exerts a negative effect on effector T cell differentiation and the associated trafficking receptor switch. Upregulated RARα levels decrease the nuclear histone acetylase (HAT) activity, and this suppresses the expression of key Teff transcription factor BATF and trafficking ...
Patrick Niekamp, Ryun Hee Kim, Adithyan Jayaraman, Nils Klement, Raymond Kostlan, Chang H. Kim   +5 more
wiley   +1 more source

Intestinal-pulmonary axis: a 'Force For Good' against respiratory viral infections. [PDF]

Front Immunol
Zhu J, Huang Z, Lin Y, Zhu W, Zeng B, Tang D.   +5 more
europepmc   +1 more source

Advances in Symbiotic Bioabsorbable Devices

Advanced Science, EarlyView.
This review focuses on recent advances in bioabsorbable devices. This review concludes innovation at the material, device, and system levels, the significant advances toward biomedical applications. This review discusses and highlights the challenges and trends in symbiotic bioresorbable electronics, and provides a new direction for the development of ...
Chang Zhu, Engui Wang, Zhou Li, Han Ouyang   +3 more
wiley   +1 more source

Unraveling the gut microbiota's role in PCOS: a new frontier in metabolic health. [PDF]

Front Endocrinol (Lausanne)
Li C, Cheng D, Ren H, Zhang T.
europepmc   +1 more source