Results 91 to 100 of about 1,071,510 (285)

The interactions between traditional Chinese medicine and gut microbiota in cancers: Current status and future perspectives

Pharmacological Research
The gut microbiota, known as the “forgotten organ” and “human second genome,” comprises a complex microecosystem. It significantly influences the development of various tumors, including colorectal, liver, stomach, breast, and lung cancers, through both ...
Xuejiao Wei, Fei Wang, Peng Tan, Huiming Huang, Zhuguo Wang, Jinxin Xie, Longyan Wang, Dongxiao Liu, Zhongdong Hu   +8 more
doaj   +1 more source

Summary of research advances on the correlation between chronic kidney disease and gastrointestinal microbiome

Linchuang shenzangbing zazhi, 2021
The incidence of chronic kidney disease（CKD）in China has remained elevated and it shows an annually rising trend.However,no radical cure is not currently available.Exploring the risk factors of CKD is a research focus of nephrology.It is generally ...
Chen Li-hua, Zhang Mei-ling, Zhong Hong-bin, Huang Ji-yi   +3 more
doaj  

Lactobacillus plantarum LP-Onlly alters the gut flora and attenuates colitis by inducing microbiome alteration in interleukin-10 knockout mice

Molecular Medicine Reports, 2017
The association between inflammatory bowel disease (IBD) and gut microbes has been widely investigated. Our previous study demonstrated that Lactobacillus plantarum LP-Onlly (LP) applied as a probiotic altered the gut flora and attenuated colitis in ...
Hongqi Chen, Yang Xia, Sibo Zhu, Jun Yang, Jing Yao, Jianzhong Di, Yong Liang, R. Gao, Wen Wu, Yongzhi Yang, Chen-zhang Shi, Desheng Hu, H. Qin, Zhigang Wang   +13 more
semanticscholar   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

The gut–eye axis: from brain neurodegenerative diseases to age-related macular degeneration

Neural Regeneration Research
Age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts vision. Unfortunately, the specific pathogenesis remains unclear, and effective early treatment options are consequently lacking.
Qianzi Jin, Suyu Wang, Yujia Yao, Qin Jiang, Keran Li   +4 more
doaj   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Pectin enhances the effect of fecal microbiota transplantation in ulcerative colitis by delaying the loss of diversity of gut flora

BMC Microbiology, 2016
BackgroundFecal microbiota transplantation (FMT) induces remission in ulcerative colitis (UC). However, the treatment effect of FMT diminishes over time.
Yao Wei, J. Gong, Weiming Zhu, H. Tian, Chao Ding, L. Gu, Ning Li, Jie‐shou Li   +7 more
semanticscholar   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

Advanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou, Anran Yan, Haowei Guo, Ping Chen, Qiang Chu   +4 more
wiley   +1 more source

Composition and immuno-stimulatory properties of extracellular DNA from mouse gut flora

World Journal of Gastroenterology, 2017
AIM To demonstrate that specific bacteria might release bacterial extracellular DNA (eDNA) to exert immunomodulatory functions in the mouse small intestine.
Ce Qi, Ya Li, R. Yu, Sheng-li Zhou, Xing-Guo Wang, G. Le, Qingzhe Jin, Hang Xiao, Jin Sun   +8 more
semanticscholar   +1 more source