High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang +6 more
wiley +1 more source
Scientific Opinion on the efficacy of Biosaf Sc 47 (Saccharomyces cerevisiae) for calves for rearing
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj +1 more source
Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 22: Suitability of taxonomic units notified to EFSA until March 2025. [PDF]
EFSA Panel on Biological Hazards (BIOHAZ) +28 more
europepmc +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of <i>Bacillus subtilis</i> DSM 32324, <i>Bacillus subtilis</i> DSM 32325 and <i>Bacillus amyloliquefaciens</i> DSM 25840 (GalliPro® Fit & GalliPro® Fit 10) for all poultry (Chr. Hansen A/S). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
europepmc +1 more source
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
New perspectives on head and neck allometry and ecomorphology in tetrapods
ABSTRACT The skull and neck are vital parts of the body, influencing feeding ecology, habitat exploitation and locomotion. Numerous studies have therefore sought to understand how the size of these segments vary with ecology and scale with overall body size.
Alice E. Maher +4 more
wiley +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of Bacillus velezensis ATCC PTA-6737 (PB6) for the renewal of the authorisations in weaned piglets, weaned minor porcine species and sows and the extension of use to all Suidae (Kemin Europe N.V). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +19 more
europepmc +1 more source
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola +11 more
wiley +1 more source

