Results 71 to 80 of about 824 (214)

Irritable bowel syndrome - An inflammatory disease involving mast cells [PDF]

, 2011
Irritable bowel syndrome (IBS) is traditionally defined as a functional disorder - that is the presence of symptoms in the absence of demonstrable pathological abnormalities. In recent times, low grade inflammatory infiltrates in both the small and large
Atkinson, Barbara, Barbara, Bischoff, Bradesi, Brandtzaeg, Camilleri, Collins, Corinaldesi, Cremon, Drossman, Drossman, Fukudo, Gao, Gibson, Guilarte, Hasler, Jun, Karamanolis, Keita, Klooker, Lee, Levy, Lobo, Mayer, Nikfar, Ohman, Piche, Powell, Shanahan, Spiller, Spiller, Spiller, Stead, Tobin, Tougas, Valent, Walker, Whorwell, Yazar, Zar   +40 more
core   +2 more sources

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 11: suitability of taxonomic units notified to EFSA until September 2019 [PDF]

, 2020
Qualified presumption of safety (QPS) was developed to provide a generic safety evaluation for biological agents to support EFSA's Scientific Panels. The taxonomic identity, body of knowledge, safety concerns and antimicrobial resistance are assessed ...
Allende, Ana, Alvarez‐Ordóñez, Avelino, Barizzone, Fulvio, Bolton, Declan, Bover‐Cid, Sara, Chemaly, Marianne, Cocconcelli, Pier Sandro, Correia, Sandra, Davies, Robert, De Cesare, Alessandra, EFSA Panel on Biological Hazards (BIOHAZ), Fernández Escámez, Pablo Salvador, Herman, Lieve, Hilbert, Friederike, Koutsoumanis, Kostas, Lindqvist, Roland, Maradona, Miguel Prieto, Nauta, Maarten, Peixe, Luisa, Querol, Amparo, Ru, Giuseppe, Simmons, Marion, Skandamis, Panagiotis, Suarez, Juan Evaristo, Suffredini, Elisabetta, Sundh, Ingvar, Vlak, Just   +26 more
core   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Safety and efficacy of Lactobacillus acidophilus D2/CSL (Lactobacillus acidophilus CECT 4529) as a feed additive for cats and dogs

EFSA Journal, 2018
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Lactobacillus acidophilus D2/CSL when used in feed ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Guido Rychen, Gabriele Aquilina, Giovanna Azimonti, Vasileios Bampidis, Maria de Lourdes Bastos, Georges Bories, Andrew Chesson, Pier Sandro Cocconcelli, Gerhard Flachowsky, Jürgen Gropp, Boris Kolar, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Alberto Mantovani, Baltasar Mayo, Fernando Ramos, Roberto Edoardo Villa, Robert John Wallace, Pieter Wester, Rosella Brozzi, Maria Saarela   +22 more
doaj   +1 more source

Biodegradable Adhesive Systems for Bio‐Integrated Applications

Advanced Science, EarlyView.
Biodegradable adhesives provide temporary yet reliable adhesion while degrading into safe, non‐toxic by‐products under physiological or environmental conditions. This review summarizes recent developments in physical and chemical adhesion mechanisms—including hydrogen bonding, catechol chemistry, amine‐carboxyl coupling, and emerging diazirine and urea
Won Bae Han, Sungkeun Han, Prashant Shivaji Shewale, Hyewon Cho, Li‐Hyun Kim, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +6 more
wiley   +1 more source

Efficacy of Fecinor® and Fecinor® plus (Enterococcus faecium) as feed additives for weaned piglets

EFSA Journal, 2015
Fecinor® and Fecinor® plus are preparations of a single strain of Enterococcus faecium. In a previous opinion on Fecinor® and Fecinor® plus, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) could not conclude on the ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Assessment of the application for renewal of the authorisation of Calsporin® (Bacillus velezensisDSM 15544) as a feed additive for weaned piglets [PDF]

[EN]Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the assessment of the application for renewal of authorisation of Calsporin®
Anguita, Montserrat, Azimonti, Giovanna, Bampidis, Vasileios, Bastos, Maria de Lourdes, Christensen, Henrik, Cocconcelli, Pier Sandro, Dusemund, Birgit, Fašmon Durjava, Mojca, Galobart, Jaume, Glandorf, Boet, Herman, Lieve, Holczknecht, Orsolya, Kouba, Maryline, López Alonso, Marta, López Puente, Secundino, Manini, Paola, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Pettenati, Elisa, Pizzo, Fabiola, Prieto Maradona, Miguel, Ramos, Fernando, Saarela, Maria, Sanz, Yolanda, Tarrés Call, Jordi, Villa, Roberto Edoardo, Woutersen, Ruud   +28 more
core   +1 more source

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 18: Suitability of taxonomic units notified to EFSA until March 2023 [PDF]

, 2023
The qualified presumption of safety (QPS) approach was developed to provide a regularly updated generic pre-evaluation of the safety of microorganisms, intended for use in the food or feed chains, to support the work of EFSA's Scientific Panels.
Sundh, Ingvar
core  

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source