Results 81 to 90 of about 113,380 (310)

Gut microbes and obesity [PDF]

Science, 2020
Metabolism A plethora of studies have uncovered correlations between gut microbiome composition and common disorders such as metabolic disease. The hope is that these correlations can be translated into therapies using mechanism-based approaches. An alternative approach is fecal microbiota transplantation (FMT), a procedure in which gut microbiota from
openaire   +1 more source

The environment within: how gut microbiota may influence metabolism and body composition

, 2010
Obesity, diabetes and consequently atherosclerotic vascular disease have become major health and public health issues worldwide. The increasing and staggering prevalence of obesity might not only be explained by nutritional habits or the reduction of ...
Vos, W.M., de, A. Vrieze, Hoekstra, J. B. L., E. G. Zoetendal, Zoetendal, E.G., F. Holleman, Vrieze, A., W. M. de Vos, J. B. L. Hoekstra, M. Nieuwdorp, Holleman, F., Zoetendal, E. G., Hoekstra, J.B., de Vos, W. M., de Vos, W.M., Nieuwdorp, M.   +15 more
core   +1 more source

Human resident gut microbe Bacteroides thetaiotaomicron regulates colonic neuronal innervation and neurogenic function

, 2020
BACKGROUND AND AIMS: As the importance of gut-brain interactions increases, understanding how specific gut microbes interact with the enteric nervous system (ENS), which is the first point of neuronal exposure becomes critical.
Blackshaw, A, Parkar, N, Parker, A, Carding, Simon, Baumard, Lucas, Parkar, Nabil, Aktar, R, Carding, S, Blackshaw, Ashley, Stentz, Regis, Brion, Arlaine, Baumard, L, Aktar, Rubina, Peiris, Madusha, Parker, Aimee, Stenz, R, Brion, A, Goldson, Andrew, Peiris, M, Goldson, A   +19 more
core   +1 more source

Gut Microbes Bifido Material for submission final

, 2022
Gut Microbes Bifido Material for submission ...
han li (12358585), Shu Jeffrey Zhu (12358648)   +1 more
core   +1 more source

Links between gut microbiome composition and fatty liver disease in a large population sample [PDF]

, 2022
Fatty liver disease is the most common liver disease in the world. Its connection with the gut microbiome has been known for at least 80 y, but this association remains mostly unstudied in the general population because of underdiagnosis and small sample
Knight Rob, Vazquez-Baeza Yoshiki, Niiranen Teemu J, Jousilahti Pekka, Havulinna Aki S, Meric Guillaume, Lahti Leo, Åberg Fredrik, Salomaa Veikko, Jain Mohit, Liu Yang, Loomba Rohit, Valsta Liisa M, Männistö Ville, Inouye Michael, Tripathi Anupriya, Ruuskanen Matti O   +16 more
core   +1 more source

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source

Improving causality in microbiome research: can human genetic epidemiology help? [version 3; peer review: 2 approved]

Wellcome Open Research, 2020
Evidence supports associations between human gut microbiome variation and multiple health outcomes and diseases. Despite compelling results from in vivo and in vitro models, few findings have been translated into an understanding of modifiable causal ...
Kaitlin H. Wade, Lindsay J. Hall
doaj   +1 more source

Benchmark of Data Processing Methods and Machine Learning Models for Gut Microbiome-Based Diagnosis of Inflammatory Bowel Disease

Frontiers in Genetics, 2022
Patients with inflammatory bowel disease (IBD) wait months and undergo numerous invasive procedures between the initial appearance of symptoms and receiving a diagnosis.
Ryszard Kubinski, Jean-Yves Djamen-Kepaou, Timur Zhanabaev, Alex Hernandez-Garcia, Stefan Bauer, Falk Hildebrand, Falk Hildebrand, Tamas Korcsmaros, Tamas Korcsmaros, Sani Karam, Prévost Jantchou, Kamran Kafi, Ryan D. Martin   +12 more
doaj   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source