Results 91 to 100 of about 746,471 (377)

Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms

open access: yesbioRxiv, 2022
Parkinson’s disease (PD) may start in the gut and spread to the brain. To investigate the role of gut microbiome, we enrolled 490 PD and 234 control individuals, conducted deep shotgun sequencing of fecal DNA, followed by metagenome-wide association ...
Zachary D. Wallen   +7 more
semanticscholar   +1 more source

THE GUT MICROBIOME AND AGING [PDF]

open access: yesInnovation in Aging, 2019
Abstract The human intestinal tract (i.e., “gut”) is inhabited by over 100 trillion microorganisms; including over 1000 species of known bacteria. These organisms have co-evolved with humans over millennia to live together for mutual benefit.
Michal M. Masternak   +2 more
openaire   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Gastrointestinal Diseases and Gut Microbiome Therapy

open access: yesXiehe Yixue Zazhi, 2022
Gut microbiome regulates host metabolism and immunity via their metabolites, secretions, and cellular components, and protects the host from pathogen invasion. Low diversity and dysfunction of the gut microbiome caused by environmental changes, unhealthy
HUANG Ziyu, ZUO Tao, LAN Ping
doaj   +1 more source

Gut microbial composition in patients with psoriasis [PDF]

open access: yes, 2018
Since the last 5–10 years the relevance of the gut microbiome on different intestinal illnesses has been revealed. Recent findings indicate the effect of gut microbiome on certain dermatological diseases such as atopic dermatitis.
Carrión, Miguel Ángel   +10 more
core   +3 more sources

Dietary macronutrients and the gut microbiome: a precision nutrition approach to improve cardiometabolic health

open access: yesGut, 2022
Accumulating evidence indicates that the gut microbiome is an important regulator of body weight, glucose and lipid metabolism, and inflammatory processes, and may thereby play a key role in the aetiology of obesity, insulin resistance and type 2 ...
K. Jardon   +3 more
semanticscholar   +1 more source

The Gut Microbiome and the Brain [PDF]

open access: yesJournal of Medicinal Food, 2014
The human gut microbiome impacts human brain health in numerous ways: (1) Structural bacterial components such as lipopolysaccharides provide low-grade tonic stimulation of the innate immune system. Excessive stimulation due to bacterial dysbiosis, small intestinal bacterial overgrowth, or increased intestinal permeability may produce systemic and/or ...
openaire   +3 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Gut microbiome diversity is associated with sleep physiology in humans.

open access: yesPLoS ONE, 2019
The human gut microbiome can influence health through the brain-gut-microbiome axis. Growing evidence suggests that the gut microbiome can influence sleep quality.
Robert P Smith   +8 more
doaj   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

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