Results 91 to 100 of about 604,531 (381)
Advanced Science, Volume 12, Issue 22, June 12, 2025.This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu +38 more
wiley +1 more source
Extrachromosomal circular DNA as a novel biomarker for the progression of colorectal cancer
Molecular MedicineBackground Extrachromosomal circular DNA (eccDNA) has potential in tumor diagnosis, particularly for improving diagnostic accuracy and early cancer detection; however, many challenges remain in its application to clinical practice. Methods We conducted a
Quanpeng Qiu +7 more
doaj +1 more source
The gut microbiome and sociability
Frontiers in NeuroscienceThe human gut microbiome plays an important role in the maturation of the neural, immune, and endocrine systems. Research data from animal models shows that gut microbiota communicate with the host's brain in an elaborate network of signaling pathways, including the vagus nerve.
Katherine T. Weber +2 more
openaire +3 more sources
Advanced Science, EarlyView.XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue +15 more
wiley +1 more source
Gut microbiome in modulating immune checkpoint inhibitors
EBioMedicine, 2022 Summary: Gut microbiome has been increasingly recognized for its influence on a diverse array of human diseases including cancer, and may also influence the outcome of cancer therapies.
Xiang Li +4 more
doaj
Gut Microbes, 2022 The gut microbiome influences the development of allergic diseases during early childhood. However, there is a lack of comprehensive understanding of microbiome-host crosstalk. Here, we analyzed the influence of gut microbiome dynamics in early childhood
Min-Jung Lee +13 more
doaj +1 more source
Multivariate Log-Contrast Regression with Sub-Compositional Predictors: Testing the Association Between Preterm Infants' Gut Microbiome and Neurobehavioral Outcomes [PDF]
arXiv, 2020 The so-called gut-brain axis has stimulated extensive research on microbiomes. One focus is to assess the association between certain clinical outcomes and the relative abundances of gut microbes, which can be presented as sub-compositional data in conformity with the taxonomic hierarchy of bacteria. Motivated by a study for identifying the microbes in
arxiv
Gut microbiome alterations in Alzheimer’s disease
Scientific Reports, 2017 Alzheimer’s disease (AD) is the most common form of dementia. However, the etiopathogenesis of this devastating disease is not fully understood. Recent studies in rodents suggest that alterations in the gut microbiome may contribute to amyloid deposition,
Nicholas M. Vogt +11 more
semanticscholar +1 more source
Potential Role of the Gut Microbiome In Colorectal Cancer Progression
Frontiers in Immunology, 2022 An increasing number of studies have revealed that the progression of colorectal cancer (CRC) is related to gut microbiome composition. Under normal conditions, the gut microbiome acts as a barrier to other pathogens or infections in the intestine and ...
Jaeho Kim, H. Lee
semanticscholar +1 more source
The Gut Microbiome and Female Health
Biology, 2022 The possession of two X chromosomes may come with the risk of various illnesses, females are more likely to be affected by osteoarthritis, heart disease, and anxiety. Given the reported correlations between gut microbiome dysbiosis and various illnesses, the female gut microbiome is worthy of exploration.
Ruqaiyyah Siddiqui +4 more
openaire +4 more sources