Results 201 to 210 of about 761,618 (380)

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

Advanced Science, EarlyView.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan, Hao Li, Jian Xue, Yourong Duan, Jin Sun, Meng Niu   +5 more
wiley   +1 more source

The gut microbiome-joint connection: implications in osteoarthritis

, 2019
Lacey J. Favazzo, Honey Hendesi, David A. Villani, Sarah Soniwala, Qurratul-Ain Dar, Eric M. Schott, Steven R. Gill, Michael J. Zuscik   +7 more
openalex   +1 more source

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source

Impact of dietary interventions on pre-diabetic oral and gut microbiome, metabolites and cytokines [PDF]

, 2023
Saar Shoer, Smadar Shilo, Anastasia Godneva, Orly Ben-Yacov, Michal Rein, Bat Chen Wolf, Maya Lotan‐Pompan, Noam Bar, Ervin I. Weiss, Yael Houri‐Haddad, Yitzhak Pilpel, Adina Weinberger, Eran Segal   +12 more
openalex   +1 more source

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

Annals of Gastroenterological Surgery, EarlyView.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki, Wataru Osumi, Kohei Taniguchi, Nahoko Kato‐Kogoe, Shoichi Sakaguchi, Shota Nakamura, Yoshiro Imai, Takashi Nakano, Takaaki Ueno, Sang‐Woong Lee   +9 more
wiley   +1 more source

The effect of 2′-fucosyllactose on simulated infant gut microbiome and metabolites; a pilot study in comparison to GOS and lactose

, 2019
Krista Salli, Heli Anglenius, Johanna Hirvonen, Ashley A. Hibberd, Ilmari Ahonen, Markku Saarinen, Kirsti Tiihonen, Johanna Maukonen, Arthur C. Ouwehand   +8 more
openalex   +1 more source

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

Advanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing, He Wang, Yangyang Sun, Xiaoquan Su, Shunyao Wu   +4 more
wiley   +1 more source

Radiation emergency medical countermeasures: Current formulary, identified gaps, and future approaches

Animal Models and Experimental Medicine, EarlyView.
Current radiation medical countermeasures primarily focus on hematopoietic acute radiation syndrome (H‐ARS) using agents like granulocyte colony‐stimulating factor (G‐CSF), granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), and romiplostim, alongside treatments for internal contamination (Prussian blue, diethylenetriamine pentaacetate [DTPA ...
Wen‐Bing Ma, Rong‐Hua Yin, Guang‐Ming Ren, Yin Zhang, Li‐Juan Li, Wei Liu, Ting Chen, Wei Zhou, Mian Zu, Rong‐Ling Yin, Xin‐Di Shi, Lei Wang, Xiao‐Ming Yang   +12 more
wiley   +1 more source

Enterotypes of the human gut microbiome

Nature, 2011
Manimozhiyan Arumugam, J. Raes, É. Pelletier, D. Paslier, Takuji Yamada, D. Mende, G. Fernandes, J. Tap, T. Bruls, Jean-Michel Batto, Marcelo Bertalan, N. Borruel, F. Casellas, Leyden Fernández, L. Gautier, T. Hansen, M. Hattori, Tetsuya Hayashi, M. Kleerebezem, K. Kurokawa, M. Leclerc, F. Levenez, C. Manichanh, H. Nielsen, T. Nielsen, N. Pons, J. Poulain, J. Qin, Thomas Sicheritz-Pontén, S. Tims, D. Torrents, Edgardo Ugarte, E. Zoetendal, Junwang, F. Guarner, O. Pedersen, W. M. Vos, S. Brunak, J. Doré, MetaHIT consortium, J. Weissenbach, S. Ehrlich, P. Bork   +42 more
semanticscholar   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source