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Current Biology, 2022
All animals, from cnidarians to humans, are colonized with microbes, and the greatest diversity and magnitude of these host-associated microorganisms resides within the intestine. Referred to as the gut microbiome, membership can be as simple as one species of bacteria or can be composed of hundreds to thousands of different microbes across the domains
Gavin A, Kuziel, Seth, Rakoff-Nahoum
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All animals, from cnidarians to humans, are colonized with microbes, and the greatest diversity and magnitude of these host-associated microorganisms resides within the intestine. Referred to as the gut microbiome, membership can be as simple as one species of bacteria or can be composed of hundreds to thousands of different microbes across the domains
Gavin A, Kuziel, Seth, Rakoff-Nahoum
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Surgical Infections, 2023
Abstract The gut has been hypothesized to be the "motor" of multiple organ dysfunction in sepsis. Although there are multiple ways in which the gut can drive systemic inflammation, increasing evidence suggests that the intestinal microbiome plays a more substantial role than previously appreciated. An English language literature review was performed to
Nathan J, Klingensmith +1 more
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Abstract The gut has been hypothesized to be the "motor" of multiple organ dysfunction in sepsis. Although there are multiple ways in which the gut can drive systemic inflammation, increasing evidence suggests that the intestinal microbiome plays a more substantial role than previously appreciated. An English language literature review was performed to
Nathan J, Klingensmith +1 more
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The gut microbiome and hypertension
Nature Reviews Nephrology, 2023A large body of evidence has emerged in the past decade supporting a role for the gut microbiome in the regulation of blood pressure. The field has moved from association to causation in the last 5 years, with studies that have used germ-free animals, antibiotic treatments and direct supplementation with microbial metabolites.
Joanne A. O’Donnell +3 more
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Overview of the Gut Microbiome
Seminars in Neurology, 2023AbstractThe human gastrointestinal tract is home to trillions of microorganisms—collectively referred to as the gut microbiome—that maintain a symbiotic relationship with their host. This diverse community of microbes grows and changes as we do, with developmental, lifestyle, and environmental factors all shaping microbiome community structure ...
Lisa, Blackmer-Raynolds +1 more
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Vitamins for the Gut Microbiome
Trends in Molecular Medicine, 2020A main target in microbiome research is the understanding and ability to safely and effectively modulate the microbiome to improve health. Hereto, we discuss the role of vitamins in relation to the gut microbiome and present a rationale for the modulation of gut microbial communities via selected systemic and colon-targeted vitamin administration.
Steinert RE, Lee YK, Sybesma W
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Gut Microbiome and Antibiotics
Archives of Medical Research, 2017Despite that the human gastrointestinal tract is the most populated ecological niche by bacteria in the human body, much is still unknown about its characteristics. This site is highly susceptible to the effects of many external factors that may affect in the quality and the quantity of the microbiome.
Tadasu, Iizumi +3 more
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The Importance of the Microbiome in the Gut
2023The recognition and study of microbes present throughout the human gastrointestinal tract is centuries old. Initially with an observational and descriptive approach, the field evolved via Koch's postulates to emphasize the germ-theory approach to the roles of the gut microbiota in human health and disease.
Morrison, Mark +2 more
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Inflammation & Allergy-Drug Targets, 2014
Since the discovery and use of the microscope in the 17(th) century, we know that we host trillions of micro-organisms mostly in the form of bacteria indwelling the "barrier organs" skin, gut, and airways. They exert regulatory functions, are in a continuous dialogue with the intestinal epithelia, influence energy handling, produce nutrients, and may ...
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Since the discovery and use of the microscope in the 17(th) century, we know that we host trillions of micro-organisms mostly in the form of bacteria indwelling the "barrier organs" skin, gut, and airways. They exert regulatory functions, are in a continuous dialogue with the intestinal epithelia, influence energy handling, produce nutrients, and may ...
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The microbiome and gut homeostasis
Science, 2022Changes in the composition of the gut microbiota are associated with many human diseases. So far, however, we have failed to define homeostasis or dysbiosis by the presence or absence of specific microbial species. The composition and function of the adult gut microbiota is governed by diet and host factors that regulate and direct microbial growth ...
Jee-Yon Lee +2 more
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The Gut Microbiome and Obesity
Current Oncology Reports, 2016The gut microbiome consists of trillions of bacteria which play an important role in human metabolism. Animal and human studies have implicated distortion of the normal microbial balance in obesity and metabolic syndrome. Bacteria causing weight gain are thought to induce the expression of genes related to lipid and carbohydrate metabolism thereby ...
George Kunnackal, John, Gerard E, Mullin
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