Results 231 to 240 of about 761,618 (380)

A model gut microbiome [PDF]

Nature Methods, 2018
openaire   +2 more sources

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

Nature Genetics, 2022
E. A. Lopera-Maya, A. Kurilshikov, A. van der Graaf, Shixian Hu, S. Andreu-Sánchez, Lianmin Chen, A. V. Vila, R. Gacesa, T. Sinha, V. Collij, Marjiolein A. Y. Klaassen, L. Bolte, M. F. B. Gois, Pieter B. T. Neerincx, Morris A. Swertz, Raul Patrick Lude Jan A. Esteban A. Ilja M. Serena Haro Aguirre-Gamboa Deelen Franke Kuivenhoven Lopera-Ma, Raúl Aguirre-Gamboa, Patrick Deelen, L. Franke, J. A. Kuivenhoven, I. Nolte, S. Sanna, H. Snieder, Morris A. Swertz, J. Vonk, C. Wijmenga, H. Harmsen, C. Wijmenga, Jingyuan Fu, R. Weersma, A. Zhernakova, S. Sanna   +31 more
semanticscholar   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Gut Microbiome and Estrogen. [PDF]

J Menopausal Med
Park SL, Kim MS, Kim TH.
europepmc   +1 more source

Gut microbiome signatures of nursing home residents carrying Enterobacteria producing extended-spectrum β-lactamases [PDF]

, 2020
Quentin Le Bastard, Guillaume Chapelet, Gabriel Birgand, Benjamin Hillmann, François Javaudin, Niki Hayatgheib, C. Bourigault, Pascale Bémer, Laure de Decker, Éric Batard, Didier Lepelletier, Emmanuel Montassier   +11 more
openalex   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, EarlyView.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

The interplay of estrogen, gut microbiome, and bone immunity in osteoporosis. [PDF]

Cell Commun Signal
Chen M, Wang J, Yang Y, He Y, Li L.
europepmc   +1 more source