Gut Virome: What's the Role in Irritable Bowel Syndrome? [PDF]
ABSTRACT The gut virome, an integral but still poorly understood component of the gut microbiota, is emerging as an important player in the pathophysiology of irritable bowel syndrome (IBS). Recent evidence suggests that alterations in virome diversity and phage–bacteria interactions contribute to gut dysbiosis, immune modulation and gut barrier ...
Rettura F +6 more
europepmc +2 more sources
Research note: The chicken gut virome: Spatiotemporal dynamics and divergent responses to antibiotic versus phytogenic supplementation [PDF]
This study employed metagenomic sequencing data to comprehensively investigate the gut virome, with a focus on the bacteriophage communities (the phageome), across intestinal regions and developmental stages in 360 chickens.
Li Yang +6 more
doaj +2 more sources
Metagenomic Analysis of the Gastrointestinal Phageome and Incorporated Dysbiosis in Children with Persistent Diarrhea of Unknown Etiology in Vietnam [PDF]
Persistent diarrhea of unknown etiology in children under 2 years of age is a common problem and poses a major challenge for the health sector. However, knowledge of the composition and dysbiosis of the intestinal phageome, phage-associated bacteriome in
Trong Khoa Dao +8 more
doaj +2 more sources
Fecal microbiota transplantation alters gut phage communities in a clinical trial for obesity [PDF]
Background Fecal microbiota transplantation (FMT) is a therapeutic intervention used to treat diseases associated with the gut microbiome. In the human gut microbiome, phages have been implicated in influencing human health, with successful engraftment ...
Michele Zuppi +7 more
doaj +2 more sources
Moderate altitude exposure impacts extensive host-microbiota multi-kingdom connectivity with serum metabolome and fasting blood glucose [PDF]
The contributions and interactions of multi-kingdom microbiota (i.e. bacteriome, mycobiome, archaeome, and phageome) with serum metabolome and host phenome in healthy individuals under moderate altitude exposure remain unclear.
Xiaoran Huang +11 more
doaj +2 more sources
The human phageome: niche-specific distribution of bacteriophages and their clinical implications [PDF]
Bacteriophages (phages) play a crucial role in shaping the composition and diversity of the human microbiome across various body niches. Recent advancements in high-throughput sequencing technologies have enabled comprehensive analysis of the human ...
Izabela Rybicka, Zuzanna Kaźmierczak
doaj +2 more sources
Host specificity and cophylogeny in the “animal-gut bacteria-phage” tripartite system [PDF]
Cophylogeny has been identified between gut bacteria and their animal host and is highly relevant to host health, but little research has extended to gut bacteriophages. Here we use bee model to investigate host specificity and cophylogeny in the “animal-
Ye Feng +13 more
doaj +2 more sources
Effects of bacteriophages on gut microbiome functionality [PDF]
The gut microbiome, composed of bacteria, fungi, and viruses, plays a crucial role in maintaining the delicate balance of human health. Emerging evidence suggests that microbiome disruptions can have far-reaching implications, ranging from the ...
Elena Kurilovich, Naama Geva-Zatorsky
doaj +2 more sources
Biases and complementarity in gut viromes obtained from bulk and virus-like particle-enriched metagenomic sequencing [PDF]
Due to varying sequencing strategies, current gut virome findings show significant variability. Specifically, bulk- and virus-like particle (VLP)-enriched metagenomic sequencing (termed bulk and VLP, respectively) present unique advantages and ...
Yun Li +6 more
doaj +2 more sources
Dietary Effects on the Gut Phageome. [PDF]
As knowledge of the gut microbiome has expanded our understanding of the symbiotic and dysbiotic relationships between the human host and its microbial constituents, the influence of gastrointestinal (GI) microbes both locally and beyond the intestine has become evident.
Howard A +3 more
europepmc +3 more sources

