Results 41 to 50 of about 609 (113)

Enteric Phageome Alterations in Patients With Type 2 Diabetes

Frontiers in Cellular and Infection Microbiology, 2021
Type 2 diabetes is a complex metabolic disease and has been shown to involve alteration of the gut microbiota. Previous studies have primarily focused on changes in the bacterial microbiome, while ignoring the phage community composition.
Qian Chen, Xiaojing Ma, Chong Li, Yun Shen, Wei Zhu, Yan Zhang, Xiaokui Guo, Jian Zhou, Chang Liu   +8 more
doaj   +1 more source

Gut microbiome and neurosurgery: Implications for treatment

Clinical and Translational Discovery, Volume 2, Issue 4, December 2022., 2022
There is a strong bidirectional link between gut microbiome dysbiosis and worsening secondary injury post‐stroke, SCI, and TBI.These deficits may be rescued by timely rejuvenation of the gut microbiome. The maintenance of a healthy microbiome plays a protective role in the setting of tumor chemotherapy and immunotherapy.
Jonathan Willman, Matthew Willman, Ramya Reddy, Anna Fusco, Sai Sriram, Yusuf Mehkri, Jude Charles, Joel Goeckeritz, Brandon Lucke‐Wold   +8 more
wiley   +1 more source

Reproducible protocols for metagenomic analysis of human faecal phageomes

Microbiome, 2018
Background Recent studies have demonstrated that the human gut is populated by complex, highly individual and stable communities of viruses, the majority of which are bacteriophages.
Andrey N. Shkoporov, Feargal J. Ryan, Lorraine A. Draper, Amanda Forde, Stephen R. Stockdale, Karen M. Daly, Siobhan A. McDonnell, James A. Nolan, Thomas D.S. Sutton, Marion Dalmasso, Angela McCann, R. Paul Ross, Colin Hill   +12 more
doaj   +1 more source

Changes in Gut Phageome and Bacteriome Following Fecal Microbiota Transfer in Patients with Intestinal Graft-Versus-Host Disease and Crohn's Disease. [PDF]

Microorganisms
Intestinal bacterial dysbiosis develops in a number of immune-mediated disorders. Fecal microbiota transfer (FMT) is considered a potentially efficient tool for restoration of the patient’s gut microbiota. The aim of our study was to trace the time course of dominant bacterial populations and some Enterobacteria phages in patients with GVHD and Crohn’s
Chukhlovin AB, Goloshchapov OV, Shchukina OB, Kharitidis AM, Zhloba AA, Subbotina TF, Kusakin AV, Kosarev OV, Tsai VV, Kalinin RS, Eismont YA, Glotov OS.   +11 more
europepmc   +3 more sources

Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19

Journal of Medical Virology, Volume 94, Issue 11, Page 5567-5573, November 2022., 2022
Abstract In December 2019, several patients were hospitalized and diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, which subsequently led to a global pandemic. To date, there are no studies evaluating the relationship between the respiratory phageome and the SARS‐CoV‐2 infection.
Carlo Ferravante, Berin S. Arslan‐Gatz, Federica Dell'Annunziata, Domenico Palumbo, Jessica Lamberti, Elena Alexandrova, Domenico Di Rosa, Oriana Strianese, Alessandro Giordano, Luigi Palo, Giorgio Giurato, Francesco A. Salzano, Massimiliano Galdiero, Alessandro Weisz, Gianluigi Franci, Francesca Rizzo, Veronica Folliero   +16 more
wiley   +1 more source

Gut Phageome Analysis Reveals Disease-Specific Hallmarks in Childhood Obesity [PDF]

, 2020
AbstractChanges in the composition of the human gut microbiome are recognized to have a significant association with obesity and metabolic syndrome. Mexico leads worldwide childhood-obesity rankings representing an epidemic problem for public health.
Shirley Bikel, Gamaliel López-Leal, Fernanda Cornejo-Granados, Luigui Gallardo-Becerra, Filiberto Sánchez, Edgar Equihua-Medina, Juan Pablo Ochoa-Romo, Blanca Estela López-Contreras, Samuel Canizales-Quinteros, Adrian Ochoa Leyva   +9 more
openaire   +1 more source

Signals triggering prophage induction in the gut microbiota

Molecular Microbiology, Volume 118, Issue 5, Page 494-502, November 2022., 2022
Gut signals inducing prophages. Abstract Compared to bacteria of the gut microbiota, bacteriophages are still poorly characterised, and their physiological importance is far less known. Temperate phages are probably a major actor in the gut, as it is estimated that 80% of intestinal bacteria are lysogens, meaning that they are carrying prophages.
Caroline Henrot, Marie‐Agnès Petit
wiley   +1 more source

Implications of oral streptococcal bacteriophages in autism spectrum disorder

npj Biofilms and Microbiomes, 2022
Growing evidence suggests altered oral and gut microbiota in autism spectrum disorder (ASD), but little is known about the alterations and roles of phages, especially within the oral microbiota in ASD subjects.
Zhan Tong, Xin Zhou, Yanan Chu, Tianxu Zhang, Jie Zhang, Xiaoyan Zhao, Zuqun Wang, Rui Ding, Qingren Meng, Jun Yu, Juan Wang, Yu Kang   +11 more
doaj   +1 more source

Current Status of Phage Therapy against Infectious Diseases and Potential Application beyond Infectious Diseases

International Journal of Clinical Practice, Volume 2022, Issue 1, 2022., 2022
Intestinal microbiota plays a key role in regulating the pathogenesis of human disease and maintaining health. Many diseases, mainly induced by bacteria, are on the rise due to the emergence of antibiotic‐resistant strains. Intestinal microorganisms include organisms such as bacteria, viruses, and fungi. They play an important role in maintaining human
Hao-Ming Xu, Wen-Min Xu, Long Zhang, Keke Zhang   +3 more
wiley   +1 more source

Long-read metagenomics of multiple displacement amplified DNA of low-biomass human gut phageomes by SACRA pre-processing chimeric reads [PDF]

DNA Research, 2021
AbstractThe human gut bacteriophage community (phageome) plays an important role in the host’s health and disease; however, the entire structure is poorly understood, partly owing to the generation of many incomplete genomes in conventional short-read metagenomics.
Yuya Kiguchi, Suguru Nishijima, Naveen Kumar, Masahira Hattori, Wataru Suda   +4 more
openaire   +2 more sources