Results 91 to 100 of about 119,881 (373)
Despite its involvement in various immune functions, including the allogeneic activation of T-lymphocytes, the relevance of calcium (Ca2+) for GVHD pathobiology is largely unknown.
Katarina Riesner +23 more
doaj +1 more source
Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool. [PDF]
Mesenchymal stem cells (MSCs) from adult somatic tissues may differentiate in vitro and in vivo into multiple mesodermal tissues including bone, cartilage, adipose tissue, tendon, ligament or even muscle. MSCs preferentially home to damaged tissues where
García-Castro, J +5 more
core
Myeloid-derived suppressor cells (MDSCs) are a naturally occurring immune regulatory population capable of suppressing inflammation, and are often associated with cancer, chronic infection and traumatic injury [1]. Growing interest in the application of MDSC therapeutically has been supported by preclinical studies in allo-graft rejection, autoimmunity
Brent H, Koehn +2 more
openaire +2 more sources
ABSTRACT The term “atypical wounds” primarily refers to lesions with immunological or cancerous etiologies. However, these wounds can also be drug‐induced. We report about a 32‐year‐old man with a 6‐year history of chronic myelogenous leukemia (CML) and chronic graft‐versus‐host disease (cGvHD) following an HLA‐compatible allogeneic stem cell ...
E. K. Stuermer +3 more
wiley +1 more source
Previous studies using genetic-deficient murine models suggest that different T-helper subsets may contribute to different types of tissue damages in graft-versus-host disease (GvHD). However, there is limited information available on the distribution of
Hsiu-Yu Lai +3 more
doaj +1 more source
Drug Hypersensitivity: A Correlation Study From Histopathology to Clinic
ABSTRACT Background Drug hypersensitivity (DH) can present with varied clinical and pathological manifestations that may mislead the referring physician. Available data regarding the concordance between pathological diagnosis and clinical findings in DH are scarce.
Olivier Philip +5 more
wiley +1 more source
On the crossroad between tolerance and posttransplant lymphoma. [PDF]
The role of the Epstein-Barr virus in the development of post-transplant lymphomas is well established. However, not all lymphomas that arise in these patients contain Epstein-Barr virus, suggesting that other cofactors are involved in tumor pathogenesis.
Nalesnik, Michael A, Starzl, Thomas E
core +1 more source
ACCELERATED CLEARANCE OF ANTI-THYMOCYTE GLOBULIN IN CHILDREN TRANSPLANTED FOR REFRACTORY CYTOPENIA OF CHILDHOOD VERSUS APLASTIC ANEMIA IS ASSOCIATED WITH INCREASED RISK OF GVHD [PDF]
Eva Koopman-Coenen +9 more
openalex +1 more source
ABSTRACT Background Hematopoietic stem cell transplant (HSCT) recipients face an increased risk of cutaneous malignancies. Chronic cutaneous graft‐versus‐host disease (cGVHD), specific to allogeneic HSCT (alloHSCT), has been proposed to further elevate this risk, though its impact on skin cancer latency and distribution remains unclear.
Amy J. Petty +2 more
wiley +1 more source
High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation. [PDF]
Despite its common use in nonmyeloablative preparative regimens, the pharmacokinetics of fludarabine are poorly characterized in hematopoietic cell transplantation (HCT) recipients and exposure-response relationships remain undefined.
Brunstein, CG +9 more
core +1 more source

