Results 101 to 110 of about 76,191 (305)
This study analysed 1498 single‐unit cord blood transplantation (CBT) cases (2000–2018) to evaluate the impact of mismatched human leukocyte antigen (HLA) immunogenicity. Results highlighted that Class I epitopes from recipient‐mismatched HLA‐B were associated with higher transplantation‐related mortality (TRM) and lower neutrophil engraftment ...
Takeshi Sugio+20 more
wiley +1 more source
GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia. [PDF]
We report graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) (a composite end point of survival without grade III-IV acute GVHD [aGVHD], systemic therapy-requiring chronic GVHD [cGVHD], or relapse) and cGVHD-free relapse-free survival ...
Abdel-Azim, Hisham+53 more
core +2 more sources
Anaplastic large cell lymphoma in children and adolescents
Summary Anaplastic lymphoma kinase (ALK)‐positive anaplastic large‐cell lymphoma (ALCL) accounts for >95% of ALCL cases in children and adolescents. The first description of ALCL as a CD30‐positive lymphoma in 1985 was followed by the detection of chromosomal translocations involving the ALK gene at chromosome 2p23.
Eric J. Lowe, Wilhelm Woessmann
wiley +1 more source
The purpose of the present study was to evaluate the mixed lymphocyte culture as a predictive assay of acute and chronic graft-versus-host disease (GVHD).
J.E.L. Visentainer+9 more
doaj +1 more source
A rapidly growing breast tumour in a young woman
JEADV Clinical Practice, EarlyView.
K. A. Zub Carlsson+6 more
wiley +1 more source
Unlike invariant natural killer T (iNKT) cells, induced pluripotent stem cell‐derived NKT (iPS‐NKT) cells exert anti‐GD2 monoclonal antibody(mAb)‐mediated antibody‐dependent cell cytotoxicity(ADCC) and exhibit CD16‐dependent cytotoxic activity and produce cytokines.
Katsuhiro Nishimura+15 more
wiley +1 more source
ABSTRACT Background To identify evidence on the use of topical CsA for ocular surface diseases (OSD). Methods A literature search was conducted following the preferred reporting items for systematic reviews and meta‐analyses (PRISMA) through June 2023 via Cochrane Central Registries, Clinical Trials Registry, Grey literature and citation searching ...
Ngozi C. Chidi‐Egboka+10 more
wiley +1 more source
Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin®) [PDF]
Modifications in the timing and dosage of immunosuppression can ameliorate the morbidity and mortality that has prevented widespread use of intestinal transplantation (ITx) in children.
Abu-Elmagd, K+8 more
core +1 more source
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou+18 more
wiley +1 more source
Serum Vitamin A Levels May Affect the Severity of Ocular Graft-versus-Host Disease
Allogeneic hematopoietic stem cell transplantation (HSCT) is a well-established therapeutic option for a range of inherited and acquired hematological disorders. However, graft-versus-host disease (GVHD) remains the leading cause of non-relapse mortality
Jiefeng Tong+5 more
doaj +1 more source