Results 111 to 120 of about 119,881 (373)

Basiliximab in the Prophylaxis of aGVHD for Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: A Prospective, Multicenter, Open‐Label, Randomized Controlled Study

American Journal of Hematology, EarlyView.
Zhenbin Wei, Rongrong Liu, Lingling Shi, Qiaochuan Li, Lianjin Liu, Baoshi Zheng, Chunjie Qin, Hong Chen, Guyun Wang, Meiqing Wu, Gaohui Yang, Ruolin Li, Zhaoping Gan, Qi Zhou, Jing Fan, Xuemei Zhou, Yinghua Chen, Zhiyu Zeng, Zhongming Zhang, Yongrong Lai   +19 more
wiley   +1 more source

Outcome parameters in studies investigating dry eye disease: A systematic literature review

Acta Ophthalmologica, EarlyView.
Abstract The development of effective therapeutics for dry eye disease (DED) is challenging due to its complex pathophysiology, heterogeneous patient presentation and the significant failure rate of previous clinical development programs. This underlines the importance of the selection of appropriate endpoints for clinical trials.
Viktoria Pai, Doreen Schmidl, Liudmyla Petric, Patrick Janku, Theresa Lindner, Ulrich Graf, Jacqueline Chua, Leopold Schmetterer, Gerhard Garhöfer   +8 more
wiley   +1 more source

Therapeutics for Graft-versus-Host Disease: From Conventional Therapies to Novel Virotherapeutic Strategies

Viruses, 2016
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has a curative potential for many hematologic malignancies and blood diseases. However, the success of allo-HSCT is limited by graft-versus-host disease (GVHD), an immunological syndrome that
Nancy Y. Villa, Masmudur M. Rahman, Grant McFadden, Christopher R. Cogle   +3 more
doaj   +1 more source

Genocopy of EVI1‐AML with paraneoplastic diabetes insipidus: PRDM16 overexpression by t(1;2)(p36;p21) and enhancer hijacking

British Journal of Haematology, EarlyView.
Summary Diabetes insipidus (DI) in patients with acute myeloid leukaemia (AML) and chromosome 3q alterations (EVI1/PRDM3/MECOM overexpression) constitutes a poorly understood paraneoplasia. A 44‐year‐old patient presented with clinical and morphological features of this syndrome but, surprisingly, disclosed the rare translocation t(1;2)(p36;p21), with ...
Julian List, Etienne Sollier, Fiona Brown‐Burke, Katherine Kelly, Dietmar Pfeifer, Valeria Shlyakhto, Kristina Maas‐Bauer, Milena Pantic, Christoph Plass, Michael Lübbert   +9 more
wiley   +1 more source

Regulatory B cells promote graft-versus-host disease prevention and maintain graft-versus-leukemia activity following allogeneic bone marrow transplantation

OncoImmunology, 2017
Regulatory B cells (Bregs) are involved in the pathogenesis of graft-versus-host disease (GVHD). However, whether Bregs can alleviate acute GVHD without compromising graft-versus-leukemia (GVL) effects remains unclear.
Yue Hu, Gan-Lin He, Xiang-Yu Zhao, Xiao-Su Zhao, Yu Wang, Lan-Ping Xu, Xiao-Hui Zhang, Xue-Zhong Yu, Kai-Yan Liu, Ying-Jun Chang, Xiao-Jun Huang   +10 more
doaj   +1 more source

Advance in Targeted Immunotherapy for Graft-Versus-Host Disease

Frontiers in Immunology, 2018
Graft-versus-host disease (GVHD) is a serious and deadly complication of patients, who undergo hematopoietic stem cell transplantation (HSCT). Despite prophylactic treatment with immunosuppressive agents, 20–80% of recipients develop acute GVHD after ...
Lingling Zhang, Jianhua Yu, Wei Wei
doaj   +1 more source

Clinical intestinal transplantation: New perspectives and immunologic considerations [PDF]

, 1998
Background: Although tacrolimus-based immunosuppression has made intestinal transplantation feasible, the risk of the requisite chronic high- dose treatment has inhibited the widespread use of these procedures.
Abu-Elmagd, K, Bueno, J, Demetris, J, Fawzy, AT, Fung, JJ, Furukawa, H, Irish, W, Lee, R, McMichael, J, Murase, N, Rakela, J, Rao, A, Reyes, J, Starzl, TE, Todo, S   +14 more
core   +1 more source

Chronic Ocular GVHD Treatment at Two Locations of a Tertiary Referral Center

Clinical Ophthalmology
Muhammad B Qureshi,1 Jose O Garcia,1 Jaxon Quillen,2 Carolyn Mead-Harvey,2 Christina Wentz,3 Cherie B Nau,4 Muriel Schornack,4 Keith Baratz,4 Sanjay V Patel,4 Joanne Shen5 1Mayo Clinic Alix School of Medicine, Scottsdale, AZ, USA; 2Department of ...
Qureshi MB, Garcia JO, Quillen J, Mead-Harvey C, Wentz C, Nau CB, Schornack M, Baratz K, Patel SV, Shen J   +9 more
doaj  

Characterization of Hepatic Dysfunction in Subjects Diagnosed With Chronic GVHD by NIH Consensus Criteria

, 2022
Alexander H. Yang, Ma Ai Thanda Han, Niharika Samala, BISHARAH S RIZVI, Rachel Marchalik, Ohad Etzion, Elizabeth C. Wright, Liang Cao, Frances T. Hakim, Elizabeth C. Jones, Devika Kapuria, Dennis D. Hickstein, Daniel H. Fowler, Jennifer A. Kanakry, Christopher G. Kanakry, David E. Kleiner, Christopher Koh, Steven Z. Pavletic, Theo Heller   +18 more
openalex   +1 more source

Effect of HLA Mismatch on Post-Transplant Infections in Allogeneic Hematopoietic Stem Cell Transplantation with PTCy-Based GvHD Prophylaxis [PDF]

, 2023
John Donald Marra, Eugenio Galli, Sabrina Giammarco, Patrizia Chiusolo, Elisabetta Metafuni, Federica Sorà, Luca Laurenti, Idanna Innocenti, Francesco Autore, Maria Assunta Limongiello, Alberto Fresa, Andrea Bacigalupo, Simona Sica   +12 more
openalex   +1 more source