Results 111 to 120 of about 76,191 (305)
Regulatory immune cells in transplantation [PDF]
, 2012 Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control the innate immune response triggered by the injured ...
Wood, Kathryn J +2 more
core +1 more source
Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases
Cell Proliferation, EarlyView.Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei +5 more
wiley +1 more source
Mouse models of graft-versus-host disease: advances and limitations
Disease Models & Mechanisms, 2011 The limiting factor for successful hematopoietic stem cell transplantation (HSCT) is graft-versus-host disease (GvHD), a post-transplant disorder that results from immune-mediated attack of recipient tissue by donor T cells contained in the transplant ...
Mark A. Schroeder, John F. DiPersio
doaj +1 more source
A Review of Demographic, Medical, and Treatment Variables Associated with Health-Related Quality of Life (HRQOL) in Survivors of Hematopoietic Stem Cell (HSCT) and Bone Marrow Transplantation (BMT) during Childhood. [PDF]
, 2017 Hematopoietic stem cell transplantation (HSCT) is a standard treatment after disease relapse and failure of conventional treatments for cancer in childhood or as a first line treatment for some high-risk cancers.
Reinfjell, Trude +2 more
core +2 more sources
Cell Proliferation, EarlyView.B2M knockout (KO) represents a crucial strategy for generating universal NK‐92MI cell products. This approach results in increased phosphorylation of SHP‐1 and inhibited phosphorylation of STAT3 and ERK, which ultimately affect their cytotoxic capabilities. SHP‐1 KO facilitates the restoration of cytotoxic function in B2M KO NK‐92MI cells.
Kuo Yu +17 more
wiley +1 more source
Chronic Ocular GVHD Treatment at Two Locations of a Tertiary Referral Center
Clinical OphthalmologyMuhammad B Qureshi,1 Jose O Garcia,1 Jaxon Quillen,2 Carolyn Mead-Harvey,2 Christina Wentz,3 Cherie B Nau,4 Muriel Schornack,4 Keith Baratz,4 Sanjay V Patel,4 Joanne Shen5 1Mayo Clinic Alix School of Medicine, Scottsdale, AZ, USA; 2Department of ...
Qureshi MB +9 more
doaj
Acute graft versus host disease
Orphanet Journal of Rare Diseases, 2007 Acute graft-versus-host disease (GVHD) occurs after allogeneic hematopoietic stem cell transplant and is a reaction of donor immune cells against host tissues. Activated donor T cells damage host epithelial cells after an inflammatory cascade that begins
Vogelsang Georgia B, Jacobsohn David A
doaj +1 more source
Blood Advances, 2019 Although differences in the incidence of chronic graft-versus-host disease (GVHD) across the races have been suggested, these have not been systematically investigated.
Yoshihiro Inamoto +14 more
doaj
Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review
European Journal of Clinical Investigation, EarlyView.Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina +8 more
wiley +1 more source