Results 191 to 200 of about 119,881 (373)

Pharmacokinetics and Safety of Single‐Dose Apraglutide in Individuals with Normal and Impaired Hepatic Function: A Phase 1, Open‐Label Trial

Clinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Intestinal failure‐associated liver disease occurs in 20% to 30% of patients with short bowel syndrome and intestinal failure (SBS‐IF). Apraglutide is a glucagon‐like peptide‐2 (GLP‐2) analog in clinical development for the treatment of patients with SBS‐IF.
Gerard Greig, Justin Hay, Patricia Valencia, Mena Boules, Tomasz Masior   +4 more
wiley   +1 more source

The role of Janus kinase signaling in graft-versus-host disease and graft versus leukemia [PDF]

, 2018
Choi, Jaebok, DiPersio, John F, Schroeder, Mark A, Staser, Karl   +3 more
core   +2 more sources

TNF-Inhibition With Etanercept For GVHD Prevention In Alternative Donor HCT: Lower TNFR1 Levels Correlate With Better Outcomes [PDF]

, 2010
Sung Won Choi, Patrick J. Stiff, Thomas Braun, James L.M. Ferrara, Kenneth R. Cooke, Y. Khaled, Carrie L. Kitko, Jennifer Lay-Luskin, Shin Mineishi, B J Nickoloff, Sophie Paczesny, Attaphol Pawarode, E. Peres, Pavan Reddy, Julia Richardson, Tulio E. Rodriguez, Scott E. Smith, Gregory A. Yanik, Joel Whitfield, John E. Levine   +19 more
openalex   +1 more source

Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect.

Blood, 2016
C. Brunstein, Jeffrey S. Miller, D. McKenna, K. Hippen, T. Defor, D. Sumstad, J. Curtsinger, M. Verneris, M. MacMillan, B. Levine, J. Riley, C. June, C. Le, D. Weisdorf, P. Mcglave, B. Blazar, J. Wagner   +16 more
semanticscholar   +1 more source

Chronic graft‐versus‐host disease in long‐term survivors of childhood leukemia

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Hematopoietic stem cell transplantation (HSCT) is a curative treatment for high‐risk childhood leukemia but may lead to chronic graft‐versus‐host disease (cGvHD), a severe long‐term complication. This study analyzed data from the LEA cohort, including 446 childhood leukemia survivors treated with allogeneic HSCT.
Paul Saultier, Gérard Michel, Anne Sirvent, Cécile Renard, Marie‐Dominique Tabone, Guy Leverger, André Baruchel, Cécile Pochon, Catherine Paillard, Charlotte Jubert, Stéphane Ducassou, Marilyne Poirée, Marion Strullu, Mony Fahd, Sandrine Visentin, Arthur Stérin, Dominique Plantaz, Justyna Kanold, Virginie Gandemer, Alexandre Theron, Nicole Raus, Sandrine Thouvenin‐Doulet, Carine Domenech, Julie Berbis, Pascal Auquier, Jean‐Hugues Dalle   +25 more
wiley   +1 more source

Cotransplantation of Mesenchymal Stem Cells Might Prevent Death from Graft-versus-Host Disease (GVHD) without Abrogating Graft-versus-Tumor Effects after HLA-Mismatched Allogeneic Transplantation following Nonmyeloablative Conditioning

, 2010
Frédéric Baron, Chantal Lechanteur, Évelyne Willems, France Bruck, Étienne Baudoux, Laurence Seidel, Jean-François Vanbellinghen, Kaoutar Hafraoui, Marie Lejeune, André Gothot, Georges Fillet, Yves Béguin   +11 more
openalex   +1 more source

Eosinophilic Gastrointestinal Disease After Pediatric Organ and Bone Marrow Transplantation

JGH Open, Volume 10, Issue 1, January 2026.
ABSTRACT Background Previous studies have shown an increased prevalence of eosinophilic gastrointestinal disease (EGID) in pediatric liver and heart transplant recipients. However, EGID after other solid organ and bone marrow transplantations has not been extensively evaluated.
Erin Sinai, Bridget E. Wilson, Melissa Pecak, Shauna Schroeder, Edward L. Swing, Cindy Bauer   +5 more
wiley   +1 more source

Supplementary Table S3 from Targeting Hedgehog Signaling with Glasdegib in Patients with Refractory Sclerotic Chronic GVHD: A Report of Two Phase I/II Trials

, 2023
Eduardo Rodríguez‐Arbolí, Catherine J. Lee, Teresa Caballero‐Velázquez, Carmen Martı́nez, Clara García-Calderón, María Reyes Jiménez‐León, María Aránzazu Bermúdez-Rodríguez, Lucía López‐Corral, Ana Triguero, Lynn Onstad, Mitchell E. Horwitz, Stefanie Sarantopoulos, Stephanie J. Lee, Josè Antonio Pérez-Simón   +13 more
openalex   +1 more source

Recipient mucosal-associated invariant T cells control GVHD within the colon

Journal of Clinical Investigation, 2018
A. Varelias, Mark D. Bunting, Kate L. Ormerod, M. Koyama, S. Olver, Jasmin Straube, R. Kuns, Renee J. Robb, A. Henden, L. Cooper, Nancy Lachner, Kate H. Gartlan, O. Lantz, L. Kjer-Nielsen, Jeffrey Y. W. Mak, D. Fairlie, A. Clouston, J. McCluskey, J. Rossjohn, S. Lane, P. Hugenholtz, G. Hill   +21 more
semanticscholar   +1 more source

Cytomegalovirus IL‐10 in Plasma as a Marker of Active Infection in Allogeneic Hematopoietic Transplant Recipients: An Exploratory Study

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT We investigated whether plasma cytomegalovirus (CMV) IL‐10 (cmvIL‐10) levels could serve as a biomarker of active CMV replication in allogeneic hematopoietic transplant recipients (allo‐HCT) in the presence or absence of letermovir (LMV) prophylaxis. A total of 189 leftover plasma samples that tested positive for CMV DNA (Alinity m CMV assay),
Ángela Sánchez‐Simarro, Eliseo Albert, Estela Giménez, Ester Colomer, Ariadna Pérez, José Luis Piñana, Carlos Solano, David Navarro   +7 more
wiley   +1 more source