Efficacy and safety of ruxolitinib for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation: a systematic review and meta-analysis. [PDF]
Xie C, Shi L, Wei Z, Lai Y, Liu R.
europepmc +1 more source
Ruxolitinib in GvHD (RIG) study: a multicenter, randomized phase 2 trial to determine the response rate of Ruxolitinib and best available treatment (BAT) versus BAT in steroid-refractory acute graft-versus-host disease (aGvHD) (NCT02396628) [PDF]
Nikolas von Bubnoff +7 more
openalex +1 more source
Chimeric Antigen Receptor T‐Cell Therapy: More Than an Anti‐Cancer Drug
ABSTRACT Initially, chimeric antigen receptor (CAR) T‐cell therapy was developed to eliminate malignant B cells in haematological B‐cell malignancies by targeting CD19 and B‐cell maturation antigen. This approach achieved notable success, resulting in (malignant) B‐cell depletion and inducing clinical remission in cancer patients.
Hannah C. M. Schenk +8 more
wiley +1 more source
Abatacept today, TMA away: protecting the endothelium. [PDF]
Ngwube A, Abraham A.
europepmc +1 more source
Abstract Background The ReCePI randomized, controlled trial compared amustaline/glutathione pathogen‐reduced (PR) and conventional red blood cell (RBC) transfusions in cardiac surgery. Study design and methods We performed a post‐hoc analysis of hemoglobin (Hb) utilization and safety outcomes.
Ian J. Welsby +11 more
wiley +1 more source
Association of donor and recipient single-nucleotide polymorphisms of interleukin-1 gene with outcomes after allogeneic hematopoietic stem cell transplantation in childhood. [PDF]
Kämpfner K, Wittig S, Gruhn B.
europepmc +1 more source
Tissue tolerance: a distinct concept to control acute GVHD severity.
Shin-Rong Wu, P. Reddy
semanticscholar +1 more source
Systemic mastocytosis (SM) with associated hematological neoplasia (SM‐AHN) is a rare and aggressive condition characterized by abnormal clonal proliferation of mast cells and the concurrent occurrence of hematologic malignancies, such as acute myeloid leukemia (AML).
Sona Vardanyan +6 more
wiley +1 more source

