Results 21 to 30 of about 76,191 (305)

Development of murine model of allogeneic bone marrow transplantation and graft-versus-host disease

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2016
Modeling of allogeneic bone marrow transplantation and graft-versus-host disease (GVHD) plays a crucial role in the improvement of transplantation procedures and testing novel immunosuppressive drugs.
I. S. Moiseev, E. A. Burmina, A. V. Botina, M. O. Popova, A. R. Muslimov, O. G. Smykova, K. V. Lepik, K. V. Melsitova, A. I. Shakirova, I. M. Barkhatov, V. V. Baikov, O. V. Galibin   +11 more
doaj   +1 more source

The thymus in GVHD pathophysiology

Best Practice & Research Clinical Haematology, 2008
A favorable outcome of allogeneic hematopoietic stem-cell transplantation (HSCT) depends on the complete reconstitution of the host's immune system. While recovery of peripheral T cells occurs in transplant recipients via both thymus-dependent and thymus-independent pathways, the regeneration of a population of phenotypically naive T cells with a broad
Krenger, W., Holländer, G. A.
openaire   +5 more sources

In vitro testing of immunosupressive effects of mesenchymal stromal cells on lymphocytes stimulated with alloantigens

Biomedical Papers, 2015
Aims: Mesenchymal stromal cells (MSC) derived from adult bone marrow or adipose tissue offer the potential to open a new frontier in medicine. MSC are involved in modulating immune response and tissue repair in vitro and in vivo.
Daniel Lysak, Tomas Vlas, Monika Holubova, Michaela Miklikova, Pavel Jindra   +4 more
doaj   +1 more source

Multi-faceted role of LRP1 in the immune system

Frontiers in Immunology, 2023
Graft versus host disease (GVHD) represents the major complication after allogeneic hematopoietic stem cell transplantation (Allo-SCT). GVHD-prone patients rely on GVHD prophylaxis (e.g.
Olga Sizova, Lisa St. John, Qing Ma, Jeffrey J. Molldrem, Jeffrey J. Molldrem   +4 more
doaj   +1 more source

Strategies in Haploidentical Stem Cell Transplantation in Adults

Turkish Journal of Hematology, 2013
Haploidentical related donors are alternative stem cell sources for patients without human leukocyte antigen (HLA)-matched related or unrelated donors.
Ulaş D. Bayraktar, Stefan O. Ciurea
doaj   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Clinical and morphological diagnostics of skin manifestations in case of graft-versus-host disease

Vestnik Dermatologii i Venerologii, 2017
The graft-versus-host disease is a life-threatening complication of allogeneic bone marrow transplantation, which demands fast and reliable diagnostics. Goal.
A. YU. Krivolapova, I. O. Smirnova, YE. V. Lisukova, I. S. Moiseyev, I. E. Belousova, V. V. Baikov   +5 more
doaj   +1 more source

Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease [PDF]

, 2019
Soluble stimulation-2 (ST2) is increased during graft-versus-host disease (GVHD), while Tregs that express ST2 prevent GVHD through unknown mechanisms.
Blazar, Bruce R., Griesenauer, Brad, Hippen, Keli L., Liu, Hong, Loschi, Michael, Paczesny, Sophie, Ramadan, Abdulraouf, Reichenbach, Dawn K., Yang, Jinfeng, Zhang, Jilu   +9 more
core   +1 more source

Phase 2 Study of Anti-Human Cytomegalovirus Monoclonal Antibodies for Prophylaxis in Hematopoietic Cell Transplantation. [PDF]

, 2020
Human cytomegalovirus (HCMV) can cause significant disease in immunocompromised patients, and treatment options are limited by toxicities. CSJ148 is a combination of two anti-HCMV human monoclonal antibodies (LJP538 and LJP539) that bind to and inhibit ...
Akard, Luke, Chemaly, Roy, Christoph, Sandra, Gerbitz, Armin, Hiemenz, John, Holler, Ernst, Hwang, William YK, Jang, Junho, Koh, Liang Piu, Lee, Dong-Gun, Logan, Aaron C, Long, Gwynn, Maertens, Johan, Mielke, Stephan, Pertel, Peter, Ramachandra, Sangana, Segal, Florencia, Smith, Kristin, Tang, Jih-Luh, Wang, Po-Nan, Winkler, Julia, Yeh, Su-Peng, Yeo, Adeline   +22 more
core   +3 more sources

CLINICALLY RELEVANT MINOR HISTOCOMPATIBILITY ANTIGENS FOR RUSSIAN PATIENTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANTATION

Медицинская иммунология, 2019
Hematopoietic stem cell transplantation (HSCT) from healthy donors is used for blood cancer treatment. Alloreactive graft-versus-host disease (GvHD) is one of the post-transplant detrimental side effects, and the main reason for GVHD after HSCT fully ...
D. S. Romaniuk, A. A. Khmelevskaya, A. M. Postovskaya, D. B. Malko, E. P. Kuzminova, E. G. Khamaganova, G. A. Efimov   +6 more
doaj   +1 more source