Results 51 to 60 of about 119,881 (373)

Immunosuppressive Effects of Multipotent Mesenchymal Stromal Cells on Graft-Versus-Host Disease in Rats Following Allogeneic Bone Marrow Transplantation

Turkish Journal of Hematology, 2013
Objective: Graft-versus-host disease (GVHD) is a major obstacle to successful allogeneic bone marrow transplantation (allo-BMT). While multipotent mesenchymal stromal cells (MSCs) demonstrate alloresponse in vitro and in vivo, they also have clinical ...
Oral Nevruz, Ferit Avcu, A. Uğur Ural, Aysel Pekel, Bahar Dirican, Mükerrem Safalı, Elvin Akdağ, Murat Beyzadeoğlu, Tayfun İde, Ali Sengül   +9 more
doaj   +1 more source

Antithymocyte Globulin Plus Post-Transplant Cyclophosphamide Combination as an Effective Strategy for Graft-versus-Host Disease Prevention in Haploidentical Peripheral Blood Stem Cell Transplantation for Children with High-Risk Malignancies

Pharmaceuticals, 2022
Haploidentical hematopoietic stem cell transplantation using post-transplant cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis has emerged as a valid alternative transplant strategy for patients lacking a suitable HLA-matched ...
Kang-Hsi Wu, Te-Fu Weng, Ju-Pi Li, Yu-Hua Chao   +3 more
doaj   +1 more source

Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. [PDF]

, 2013
Gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), graft-versus-host disease (GVHD), and inflammatory bowel diseases such as ulcerative colitis and Crohn's disease are common human gastrointestinal diseases that share inflammation as a key
Bortner, James D, Falk, Gary W, Hartman, Kira G, Lynch, John P, Martín, Martín G, Rustgi, Anil K, Yu, Jian   +6 more
core   +2 more sources

GvHD-Prophylaxe

, 2020
ZusammenfassungDas Kapitel 33 beinhaltet eine Zusammenstellung der am Universitätsklinikum Freiburg verwendeten Tumortherapie- und ggf. Studien-Protokolle zur Prophylaxe der Graft versus Host Disease (GvHD). Der Kapitelinhalt orientiert sich an aktuellen Leitlinien und Therapieempfehlungen und spiegelt detailliert die Therapieabläufe inkl ...
Monika Engelhardt, Roland Mertelsmann, Justus Duyster   +2 more
openaire   +1 more source

Dexamethasone palmitate ameliorates macrophages-rich graft-versus-host disease by inhibiting macrophage functions. [PDF]

PLoS ONE, 2014
Macrophage infiltration of skin GVHD lesions correlates directly with disease severity, but the mechanisms underlying this relationship remain unclear and GVHD with many macrophages is a therapeutic challenge.
Satoshi Nishiwaki, Takayuki Nakayama, Makoto Murata, Tetsuya Nishida, Seitaro Terakura, Shigeki Saito, Tomonori Kato, Hiroki Mizuno, Nobuhiko Imahashi, Aika Seto, Yukiyasu Ozawa, Koichi Miyamura, Masafumi Ito, Kyosuke Takeshita, Hidefumi Kato, Shinya Toyokuni, Keisuke Nagao, Ryuzo Ueda, Tomoki Naoe   +18 more
doaj   +1 more source

Butyrogenic bacteria after acute graft-versus-host disease (GVHD) are associated with the development of steroid-refractory GVHD.

Blood Advances, 2019
The presence of butyrogenic bacteria after the onset of acute GVHD associates with subsequent steroid-refractory GVHD or chronic GVHD. Butyrate inhibits human colonic stem cells from forming an intact epithelial monolayer.
J. Golob, Martha Demeules, Tillie Loeffelholz, Z. Quinn, M. Dame, Sabrina S. Silvestri, Michael C. Wu, T. Schmidt, T. Fiedler, Matthew J. Hoostal, M. Mielcarek, Marco Mielcarek, J. Spence, S. Pergam, S. Pergam, D. Fredricks, D. Fredricks   +16 more
semanticscholar   +1 more source

Alteration in the Skin Microbiome in Cutaneous Graft Versus Host Disease

Acta Dermato-Venereologica, 2021
Graft versus host disease (GVHD) is a common complication of haematopoietic stem cell transplantation. This study examined the cutaneous microbiome in relation to the pathogenesis of cutaneous GVHD.
Ying Gu, Jing Sun, Kun Li, Xia Wu, Jianzhong Zhang   +4 more
doaj   +1 more source

Ruxolitinib for the treatment of patients with steroid-refractory GVHD: an introduction to the REACH  trials.

Immunotherapy, 2018
For patients with hematologic malignancies and disorders, allogeneic hematopoietic stem cell transplantation offers a potentially curative treatment option.
M. Jagasia, R. Zeiser, M. Arbushites, P. Delaite, B. Gadbaw, N. Bubnoff   +5 more
semanticscholar   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

Comparison of characteristics and outcomes of late acute and NIH chronic GVHD between Japanese and white patients

Blood Advances, 2019
Although differences in the incidence of chronic graft-versus-host disease (GVHD) across the races have been suggested, these have not been systematically investigated.
Yoshihiro Inamoto, Jennifer White, Reiko Ito, Paul J. Martin, Giancarlo Fatobene, Ayumu Ito, Takashi Tanaka, Saiko Kurosawa, Sung-Won Kim, Merav Bar, Mohamed L. Sorror, Brenda M. Sandmaier, Stephanie J. Lee, Takahiro Fukuda, Mary E.D. Flowers   +14 more
doaj   +1 more source