Results 61 to 70 of about 76,191 (305)
Malnutrition in patients with chronic GVHD [PDF]
Bone Marrow Transplantation, 2014 Malnutrition is a known complication of chronic GVHD (cGVHD), but has not been well described in the context of organ-specific manifestations and the recent National Institutes of Health (NIH) criteria. Here, 210 cGVHD patients were analyzed, in a cross-sectional study design, for demographics, transplant-related history, clinical assessments, symptoms,
Lana Grković +16 more
openaire +3 more sources
Classical and Late‐Onset SOS/VOD After Allogeneic HSCT: A Japanese Transplant Registry Analysis
American Journal of Hematology, EarlyView.ABSTRACT Sinusoidal obstruction syndrome/veno‐occlusive disease (SOS/VOD) is a lethal complication of allogeneic hematopoietic stem cell transplantation (allo‐HSCT). According to the 2016 European Society for Blood and Marrow Transplantation criteria, SOS/VOD is classified into classical SOS/VOD and late‐onset SOS/VOD, but their similarities and ...
Kyoko Masuda +20 more
wiley +1 more source
Mucormycosis in solid organ transplant recipients (clinical cases and literature review)
Вестник трансплантологии и искусственных органовMucormycosis is a severe mycotic infection with high mortality among immunocompromised patients. Its in- cidence in solid organ transplant recipients is 2–8% of all invasive fungal infections.
S. N. Khostelidi +8 more
doaj +1 more source
TLI in refractory chronic GVHD [PDF]
Bone Marrow Transplantation, 2012 Refractory chronic GVHD (cGVHD) remains a major cause of morbidity after transplantation. Many drugs are used but there is no consensus on the standard of care. We investigated the efficacy of TLI in corticosteroid-refractory cGVHD. We analyzed retrospectively 31 patients receiving one or more TLI session for refractory cGVHD from 2000 to 2007.
Luca Castagna +7 more
openaire +2 more sources
Dose-adapted post-transplant cyclophosphamide for HLA-haploidentical transplantation in Fanconi anemia. [PDF]
, 2017 We developed a haploidentical transplantation protocol with post-transplant cyclophosphamide (CY) for in vivo T-cell depletion (TCD) using a novel adapted-dosing schedule (25 mg/kg on days +3 and +4) for Fanconi anemia (FA).
Bonfim, C +8 more
core +2 more sources
New interleukin-15 superagonist (IL-15SA) significantly enhances graft-versus-tumor activity. [PDF]
, 2017 Interleukin-15 (IL-15) is a potent cytokine that increases CD8+ T and NK cell numbers and function in experimental models. However, obstacles remain in using IL-15 therapeutically, specifically its low potency and short in vivo half-life.
Alpdogan, Onder +8 more
core +3 more sources
Application of humanized mice in the safety experiments of antibody drugs
Animal Models and Experimental Medicine, EarlyView.The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun +9 more
wiley +1 more source
Frontiers in Immunology, 2020 Despite its involvement in various immune functions, including the allogeneic activation of T-lymphocytes, the relevance of calcium (Ca2+) for GVHD pathobiology is largely unknown.
Katarina Riesner +23 more
doaj +1 more source
Blood, 2011 Patients with aplastic anemia (AA) derive no benefit from GVHD. In this issue of Blood , Marsh and colleagues report that conditioning with an alemtuzumab-containing regimen almost completely prevented GVHD in AA patients who received a transplant of either bone marrow (BM) or peripheral ...
openaire +3 more sources
Arthritis &Rheumatology, EarlyView.Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh +12 more
wiley +1 more source