Results 141 to 150 of about 68,978 (241)

Therapeutic vaccination using HPV 16 E7 to eradicate CIN3. [PDF]

, 2019
Tewari, Krishnansu S
core  

Initial Treatment and Referral Patterns for Acute Facial Palsy: Insights From Emergency Department Practices

The Laryngoscope, EarlyView.
ABSTRACT Objectives To investigate variations in Bell's Palsy treatment and referrals within the Emergency Department (ED), with a focus on sociodemographic and provider‐related factors. Methods A retrospective cohort review was performed including patients with a new diagnosis of Bell's Palsy or acute facial paralysis treated at a single, tertiary ...
Christine C. Little, Rahul K. Sharma, Alexander Barna, Priyesh N. Patel, Scott J. Stephan, Shiayin F. Yang   +5 more
wiley   +1 more source

Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials [PDF]

, 2017
et al,, Mutch, David G
core   +1 more source

A Transcriptional Variant of Anaplastic Lymphoma Kinase Promotes Apoptosis in Ovarian High‐Grade Serous Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT The current study aims to delineate the role of a novel anaplastic lymphoma kinase (ALK) transcript, ALKATI, in ovarian high‐grade serous carcinoma (HGSC). Overexpressed ALKATI exhibited both cytoplasmic and nuclear localization in HGSC cells, whereas full‐length ALK was predominantly cytoplasmic.
Ako Yokoi, Daigo Yoshimori, Yasuko Oguri, Miki Hashimura, Makoto Saegusa   +4 more
wiley   +1 more source

The implementation and side effect management of immune checkpoint inhibitors in gynecologic oncology: a JAGO/NOGGO survey. [PDF]

BMC Cancer
Riedel M, Herrmann H, Bartl T, Rossner AM, Tatzber A, Flethe C, Zocholl D, Schmalfeldt B, Sehouli J, Pietzner K.   +9 more
europepmc   +1 more source

Geometrically focused training and evaluation of organs‐at‐risk segmentation via deep learning

Medical Physics, EarlyView.
Abstract Background Deep learning methods are promising in automating segmentation of organs at risk (OARs) in radiotherapy. However, the lack of a geometric indicator for dosimetry accuracy remains to be a problem. This issue is particularly pronounced in specific radiotherapy treatments where only the proximity of structures to the radiotherapy ...
Ruiyan Ni, Elizabeth Chuk, Kathy Han, Jennifer Croke, Anthony Fyles, Jelena Lukovic, Michael Milosevic, Benjamin Haibe‐Kains, Alexandra Rink   +8 more
wiley   +1 more source

Clinical practice guidelines for ovarian cancer: an update to the Korean Society of Gynecologic Oncology guidelines. [PDF]

J Gynecol Oncol
Lee B, Chang SJ, Kwon BS, Son JH, Lim MC, Kim YH, Lee SW, Choi CH, Eoh KJ, Lee JY, Lee YY, Suh DH, Kim YB.   +12 more
europepmc   +1 more source

Activated immune infiltrates expand opportunities for targeted therapy in p53‐abnormal endometrial carcinoma

The Journal of Pathology, EarlyView.
Abstract Tumor protein p53 mutated/abnormal (p53abn) endometrial carcinomas account for over 50% of deaths but comprise only 15% of all endometrial carcinomas. Most patients show limited response to standard‐of‐care chemotherapy with or without radiotherapy, and only a minority of cases are amenable to targeted therapies like poly‐ADP ribose polymerase
Spencer D Martin, Shelby Thornton, Christine Chow, Katy Milne, Juliana Sobral de Barros, Kayleigh A Morris, Samuel Leung, Amy Jamieson, Brad H Nelson, Dawn R Cochrane, David G Huntsman, C Blake Gilks, Lien Hoang, Jessica N McAlpine, Allen W Zhang   +14 more
wiley   +1 more source

Clinical practice guidelines for cervical cancer: an update of the Korean Society of Gynecologic Oncology Guidelines. [PDF]

J Gynecol Oncol
Yoo JG, Lee SJ, Nam EJ, No JH, Park JY, Song JY, Shin SJ, Yun BS, Park ST, Lee SH, Suh DH, Kim YB, Lee KH.   +12 more
europepmc   +1 more source

Cystathionine gamma‐lyase‐mediated hypoxia inducible factor 1‐alpha expression drives clear cell ovarian cancer progression

The Journal of Pathology, EarlyView.
Abstract Clear cell ovarian cancer (CCOC) is the second most common ovarian cancer subtype, accounting for 5%–11% of ovarian cancers in North America. Late‐stage CCOC is associated with a worse prognosis compared to other ovarian cancer histotypes, a challenge that has seen limited progress in recent decades.
Amal M EL‐Naggar, Yuqin Li, Busra Turgu, Yuchen Ding, Longyijie Wei, Shary Yuting Chen, Genny Trigo‐Gonzalez, Forouh Kalantari, Rodrigo Vallejos, Branden Lynch, Janine Senz, Amy Lum, J Maxwell Douglas, Clara Salamanca, Shelby Thornton, Yimei Qin, Kiran Parmar, Sandra E Spencer, Samuel Leung, Michelle MM Woo, Paul J Yong, Hai‐Feng Zhang, Christopher S Hughes, Gian Luca Negri, Yemin Wang, Gregg B Morin, Poul H Sorensen, David G Huntsman   +27 more
wiley   +1 more source