Results 261 to 270 of about 491,703 (337)

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Provider perspectives on caring for patients with limited English proficiency-a national survey of the Society of Gynecologic Oncology. [PDF]

Gynecol Oncol Rep
Folsom SM, Olawaiye AB, Taylor SE.
europepmc   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Role of COVID-19 Vaccine in the Management of Gynecologic Oncology Lymphadenopathies. [PDF]

Int J Environ Res Public Health
Fernandez Sanahuja L, Miralpeix E, Solé Sedeño JM, Baucells M, Fabregó B, Sierra A, Mancebo G.   +6 more
europepmc   +1 more source

Clinical Advances and Challenges in Dose Constraints for Organs at Risk in Proton Therapy: A Systematic Review of the Last Decade's Literature

Precision Radiation Oncology, EarlyView.
This systematic review synthesizes decade‐long evidence from peer‐reviewed literature and clinical guidelines, critically evaluating current understanding of OARs tolerance in proton therapy. Abstract Proton beam therapy has demonstrated significant clinical efficacy across multiple malignancies, primarily attributed to its distinct physical dose ...
Jinghao Duan, Cheng Tao, Shizhang Wu, Chengqiang Li, Jinhu Chen, Tianyuan Dai, Yunyi Fan, Tong Bai, Xiangjuan Meng, Tian Kong, Jian Zhu   +10 more
wiley   +1 more source

Prognostic Value of a Joint K‐PD Model With Tumor Size Dynamics and CA‐125 Kinetics in Recurrent Ovarian Cancer Patients: BOLD Phase II GINECO Study

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT In patients with recurrent advanced ovarian cancer, there is a need for companion tests to guide the development of innovative chemotherapy‐free treatments. The modeled longitudinal CA‐125 ELIMination rate constant K KELIM‐B was a major prognostic factor for progression‐free survival (PFS) and overall survival (OS) in recurrent advanced ...
Aurore Carrot, Pauline Corbaux, Olivier Colomban, Coriolan Lebreton, Laurence Gladieff, Olivier Tredan, Frédéric Selle, Cyril Abdeddaim, Alexandra Leary, Véronique D'Hondt, Coraline Dubot, Thibaut Reverdy, Benoit You, Gilles Freyer   +13 more
wiley   +1 more source

Plasmonic Mesoporous Gold‐Based SERS Biosensor for Ovarian Cancer‐Derived Extracellular Vesicles

Small, EarlyView.
The nanoengineered mesoporous gold (mAu)‐based SERS platform enables rapid, sensitive detection of PLAP‐positive extracellular vesicles (EVs) in ovarian cancer (OC), with detection limits as low as 100 EVs mL−1. Achieving over 80% sensitivity and 98% specificity in clinical samples, this cost‐effective, non‐invasive tool shows promise for early cancer ...
Javeria Bashir, Mostafa Kamal Masud, Asep Sugih Nugraha, Chia‐Hung Liu, Arya Vasanth, Aditya Ashok, S M Azad Hossain, Emtiaz Ahmed, Tanja Pejovic, Terry Morgan, John Hooper, Andrew Lai, Dominic Guanzon, Yusuf Valentino Kaneti, Md Shahriar A. Hossain, Carlos Salomon, Yusuke Yamauchi   +16 more
wiley   +1 more source

Geographic Disparities in Gynecologic Oncology Clinical Trial Availability in the US.

JAMA Netw Open
Boland MR, Tubridy E, Solorzano SS, Simpkins F, Smith AJB, Ko EM.   +5 more
europepmc   +1 more source

Screening log: Challenges in community patient recruitment for gynecologic oncology clinical trials. [PDF]

Contemp Clin Trials Commun
Ratnaparkhi R, Doolittle GC, Krebill H, Springer M, Calhoun E, Jewell A, Mudaranthakam DP.   +6 more
europepmc   +1 more source

Optical Coherence Tomography Angiography in the Assessment of Vulvar Lichen Sclerosus Vascularity and Epithelial Thickness In Vivo

Translational Biophotonics, EarlyView.
Optical Coherence Tomography Angiography in the Assessment of Vulvar Lichen Sclerosus ABSTRACT Vulvar lichen sclerosus is a chronic inflammatory skin condition that leads to scarring and an increased risk of squamous cell carcinoma. It presents clinically as atrophic white patches or plaques, often with associated fissures, erosions, hyperkeratosis ...
Raksha Sreeramachandra Murthy, Christina N. Kraus, Felicia Lane, Zhongping Chen   +3 more
wiley   +1 more source