Results 111 to 120 of about 838,521 (380)

eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR‐Mediated Metabolic Rewiring

Advanced Science, EarlyView.
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal, Minal Nenwani, Ishaque Pulikkal Kadamberi, Sudhir Kumar, Olamide Animasahun, Jasmine George, Shirng‐Wern Tsaih, Prachi Gupta, Mona Singh, Anjali Geethadevi, Chandrima Dey, Noah Meurs, Ajay Shankaran, Pradeep Chaluvally Raghavan, Deepak Nagrath, Sunila Pradeep   +15 more
wiley   +1 more source

Predicting Infection Risk in Acute Compartment Syndrome: A Nomogram Model Based on Admission Blood Indicators

International Journal of General Medicine
JianJun Song,1 YueJun Liu,2 Meng Yang,3 Yan Li,1 YueYue Hu4 1Emergency ICU, Gynecology Department, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, People’s Republic of China; 2Department of Gynecology, Gynecology Department ...
Song J, Liu Y, Yang M, Li Y, Hu Y
doaj  

Assisted reproductive technology in Japan: a summary report for 2015 by The Ethics Committee of The Japan Society of Obstetrics and Gynecology

Reproductive Medicine and Biology, 2017
The Japan Society of Obstetrics and Gynecology (JSOG) implemented an assisted reproductive technology (ART) registry system in 1986. Here are reported the characteristics and treatment outcomes of ART cycles that were registered in 2015.
H. Saito, S. Jwa, A. Kuwahara, Kazuki Saito, T. Ishikawa, O. Ishihara, K. Kugu, R. Sawa, K. Banno, M. Irahara   +9 more
semanticscholar   +1 more source

Lasers in Gynecology [PDF]

Obstetrics & Gynecology
The first published reports on the use of laser for cervical pathology date back to 1973. Technical advancements in flexible and rigid laser fibers revolutionized video laser laparoscopy in the 1990s. Fractionated lasers have been used to treat vulvovaginal symptoms associated with genitourinary syndrome of menopause, lichen sclerosus, and urinary ...
Iglesia, Cheryl B, Choi, Jennie Eunsook, Tadir, Yona   +2 more
openaire   +3 more sources

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

Advanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen, Huafeng Geng, Yang Zheng, Hongyang Xie, Rui Qin, Junyang Chen, Cong Ye   +6 more
wiley   +1 more source

Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome

Drug Design, Development and Therapy
Zhenzhen Cao,1,* Qin Zhou,1,* Jie An,1,* Xiaojing Guo,1 XiaoFang Jia,1 Yuena Qiu2 1Department of Gynecology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, Jiangsu, 215300, People’s Republic of China; 2Department of ...
Cao Z, Zhou Q, An J, Guo X, Jia X, Qiu Y
doaj  

Work-Related Musculoskeletal Disorders and Risk Factors among Chinese Medical Staff of Obstetrics and Gynecology

International Journal of Environmental Research and Public Health, 2017
Medical staff in the department of obstetrics and gynecology are a group of professionals reportedly at high risk of work-related musculoskeletal disorders (WMSD), however, little is known about the current status of this problem in China.
Jingjing Wang, Yabin Cui, Lihua He, Xiangrong Xu, Z. Yuan, Xianning Jin, Zhimin Li   +6 more
semanticscholar   +1 more source

Contemporary and Historical Evidence to Suggest that Women’s Preference for Age at Birth of First Child Remains Consistent Across Time [PDF]

, 2014
Women’s ability to reproduce is restricted by menarche and menopause. First children are, however, not typically born until some years after the onset of puberty. Other factors therefore contribute towards this delay. In this context, women’s hips do not
Brewer, Gayle, Hendrie, Colin A., Lewis, Hannah, Mills, Francesca   +3 more
core   +2 more sources

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

Advanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye, Anning Zhao, Xia Li, Yanqing Hao, Dong Huang, Jianmin Chen, Tiantian Li, Yangyang Dai, Wenchao Sun, Lie Ma, Songying Zhang, Liaobing Xin   +11 more
wiley   +1 more source

The Teaching of Obstetrics and Gynecology from the Point of View of a General Practitioner [PDF]

, 1919
Ricky W. Johnstone
  +9 more sources