Results 131 to 140 of about 402,905 (265)

Gynecologic Pathology [PDF]

Surgical Pathology Clinics, 2016
Blaise A, Clarke, W Glenn, McCluggage
openaire   +2 more sources

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

Indication-dependent heterogeneity in the effect of double-suture cerclage: concerns over indication classification and a call for stratified analysis. [PDF]

Arch Gynecol Obstet
Park YJ, Park MI.
europepmc   +1 more source

Utilization of immune checkpoint inhibitors for the treatment of cancer in Scotland, 2018–2024: A national retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of the study is to describe the use of immune checkpoint inhibitors (ICIs) for the treatment of cancer in Scotland. Methods The retrospective observational cohort study included patients aged 18 years or older who commenced treatment with an ICI in Scotland between 1 January 2018 and 31 December 2024.
Tanja Mueller, Christine Crearie, Liya Lu, Jiafeng Pan, Fraser N. Sneden, David Martin, Amanj Kurdi, Catherine S. Thomson, Julie Clarke, Marion Bennie   +9 more
wiley   +1 more source

Obstetric and Neonatal Outcomes Following Immediate Delivery Versus Expectant Management in Pregnant Women With Preterm Premature Rupture of Membranes During the Late Preterm Period in Korea. [PDF]

J Korean Med Sci
Kwon H, Kwon JY, Kang S, Ko HS, Kwon HS, Oh KJ, Oh SY, Lee MY, Choi SR, Han YJ, Sul AR, Jung Y, Kim J, Park JJ, Lee J, Kim YN, Yang JI.   +16 more
europepmc   +1 more source

Obstetrics and gynecology care as an opportunity for penicillin allergy testing: Results from a novel survey. [PDF]

Dialogues Health
Patel AR, Vazquez CL, Kobak WH, Class QA.   +3 more
europepmc   +1 more source

A Rare Case of Leiomyoma-Associated Cutaneous Sinus Tract Secondary to an Infected Uterine Leiomyoma Without Prior Myomectomy. [PDF]

Case Rep Obstet Gynecol
Tjokroprawiro BA, Novitasari K, Ulhaq RA, Sulistya HA, Iskandar TM.   +4 more
europepmc   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Subtypes of Hypertension 2 to 7 Years After First Pregnancy. [PDF]

Hypertension
Brubaker LH, Catov JM, Bairey Merz CN, Barnes S, Barone Gibbs B, Booker W, Chung JH, Greenland P, Grobman WA, Khan SS, Lane A, Levine LD, McNeil RB, Miller EC, Muldoon MF, Ray M, Saade GR, Scifres CM, Silver RM, Simhan H, Yee LM, Hauspurg A.   +21 more
europepmc   +1 more source

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source