Results 111 to 120 of about 706,480 (354)

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

Advanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang, Nan Zhang, Xisong Liang, Jie Wen, Ziyu Dai, Wantao Wu, Shuyu Li, Songshan Feng, Zaoqu Liu, Zhiwei Xia, Peng Luo, Quan Cheng   +11 more
wiley   +1 more source

Factors Influencing Burnout Syndrome in Obstetrics and Gynecology Physicians

BioMed Research International, 2017
Aim To identify the influence of environmental, personality, and alexithymia factors on burnout syndrome among obstetrics and gynecology physicians.
M. Iorga, Vladimir Socolov, D. Muraru, C. Dîrţu, Camelia Soponaru, C. Ilea, D. Socolov   +6 more
semanticscholar   +1 more source

PROGRESS IN GYNECOLOGY. [PDF]

JAMA: The Journal of the American Medical Association, 1899
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openaire   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Association Between Atherogenic Index of Plasma and Endometriosis: Evidence from NHANES 1999–2006

International Journal of Women's Health
Liwen Liu,1 Gaosheng Su,1 Jie Rao,1 Juanbao Peng,1 Xiu Lin,2 Yujie Huang,2 Feng Liang,2 Chuanxia Feng,1 Zhong Lin2 1Department of Anesthesia, The Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China ...
Liu L, Su G, Rao J, Peng J, Lin X, Huang Y, Liang F, Feng C, Lin Z   +8 more
doaj  

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

A Nomogram Based on Fibrinogen-to-Neutrophil Ratio as a Novel Predictor of Lymph Node Metastasis in Patients with Cervical Cancer and Type 2 Diabetes Mellitus

Cancer Management and Research
Hongying Kuang,1,* Dongxia Yang,2,* Ruoyao Lin,3 Yaling Tang,4 Yongli Luo,3 Shuwen Wang,5 Tingting Xia,5 Ge Lou,6 Hong Chen4 1Department of Gynecology, The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin ...
Kuang H, Yang D, Lin R, Tang Y, Luo Y, Wang S, Xia T, Lou G, Chen H   +8 more
doaj  

The Experience of Organ-preserving Treatment of Cervical Cancer

Сеченовский вестник, 2015
The article analyzes the results of organ-preserving treatment of patients suff ering from cancer of the cervix. On the basis of literature data and own results it is concluded that conserving therapy of early cervical cancer pathology not only cures the
A. I. Ishchenko, A. A. Ishchenko, Ya. R. Malysheva, A. V. Kochatkov   +3 more
doaj  

Development of the specific supportive care needs scale for patients with gynecologic cancer and its reliability and validity test

Huli yanjiu, 2020
ObjectiveTo develop the specific supportive care needs scale for patients with gynecological cancer(SSCNS⁃G),and to test its reliability and validity.MethodsThe item pool was established by literature review,qualitative interview and relevant scales ...
GE Xiaoling, SONG Yongxia, YU Miao, HE Hongye, HONG Jingfang   +4 more
doaj  

Clinical limitations of the International Federation of Gynecology and Obstetrics (FIGO) classification of uterine fibroids

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2017
To determine the reproducibility of classifying uterine fibroids using the 2011 International Federation of Gynecology and Obstetrics (FIGO) staging system.
S. Laughlin-Tommaso, G. Hesley, M. Hopkins, Kathleen R. Brandt, Yunxiao Zhu, Elizabeth A. Stewart   +5 more
semanticscholar   +1 more source