Results 81 to 90 of about 683,972 (341)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Predicting Infection Risk in Acute Compartment Syndrome: A Nomogram Model Based on Admission Blood Indicators

International Journal of General Medicine
JianJun Song,1 YueJun Liu,2 Meng Yang,3 Yan Li,1 YueYue Hu4 1Emergency ICU, Gynecology Department, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, People’s Republic of China; 2Department of Gynecology, Gynecology Department ...
Song J, Liu Y, Yang M, Li Y, Hu Y
doaj  

The Experience of Organ-preserving Treatment of Cervical Cancer

Сеченовский вестник, 2015
The article analyzes the results of organ-preserving treatment of patients suff ering from cancer of the cervix. On the basis of literature data and own results it is concluded that conserving therapy of early cervical cancer pathology not only cures the
A. I. Ishchenko, A. A. Ishchenko, Ya. R. Malysheva, A. V. Kochatkov   +3 more
doaj  

Education level is associated with the occurrence and timing of hysterectomy: A cohort study of Canadian women

Acta Obstetricia et Gynecologica Scandinavica
Introduction Hysterectomy is a common surgery with discernible practice variations that could be influenced by socioeconomic factors. We examined the association between level of educational attainment and the occurrence and timing of hysterectomy in ...
Erin A. Brennand, Natalie V. Scime, Beili Huang, Pauline McDonagh Hull   +3 more
doaj   +1 more source

Characteristics Symptoms of Imminent Eclampsia: A case Referent Study from a Tertiary Hospital in Tanzania [PDF]

, 2012
\ud \ud Maternal mortality in developing coun- tries is unacceptably high with eclampsia being con- sistently among the top causes. As yet, primary pre- vention of this complication is not possible since causes of pre-eclampsia are largely unknown and ...
France, John, Muganyizi, Projestine S.
core  

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome

Drug Design, Development and Therapy
Zhenzhen Cao,1,* Qin Zhou,1,* Jie An,1,* Xiaojing Guo,1 XiaoFang Jia,1 Yuena Qiu2 1Department of Gynecology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, Jiangsu, 215300, People’s Republic of China; 2Department of ...
Cao Z, Zhou Q, An J, Guo X, Jia X, Qiu Y
doaj  

Next‐generation monitoring in obstetrics: Assessing the accuracy of non‐piezo portable ultrasound technology

Acta Obstetricia et Gynecologica Scandinavica
Introduction The emergence of handheld ultrasound devices capable of connecting to cell phones or tablets heralds a significant advancement in medical technology, particularly within the field of obstetrics.
Ruben Plöger, Charlotte Behning, Adeline Walter, Jorge Jimenez Cruz, Ulrich Gembruch, Brigitte Strizek, Florian Recker   +6 more
doaj   +1 more source

Old School Catalog 1909-10, Chicago College of Medicine and Surgery [PDF]

, 1909
https://scholar.valpo.edu/oldschoolcatalogs/1019/thumbnail ...
Valparaiso University
core   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source