Results 21 to 30 of about 57,372 (130)

Amisulpride and l‐DOPA modulate subcortical brain nuclei connectivity in resting‐state pharmacologic magnetic resonance imaging

Human Brain Mapping, Volume 41, Issue 7, Page 1806-1818, May 2020., 2020
Abstract The precise understanding of the dopaminergic (DA) system and its pharmacological modifications is crucial for diagnosis and treatment of neuropsychiatric disorders, as well as for understanding basic processes, such as motivation and reward. We probed the functional connectivity (FC) of subcortical nuclei related to the DA system according to
Oliver Grimm, Vera Kopfer, Lea Küpper‐Tetzel, Vera Deppert, Magdalena Kuhn, Moritz de Greck, Andreas Reif   +6 more
wiley   +1 more source

Die Bedeutung des anterioren Gyrus cinguli in der Pathogenese schizophrener Erkrankungen [PDF]

, 2005
Der anteriore Gyrus cinguli (ACC) ist eine zentrale Struktur des rostralen limbischen Systems, die in den letzten Jahren zunehmend in das Interesse der psychiatrischen Forschung rückte.
Watz, Dorothee
core   +1 more source

Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis [PDF]

, 2005
In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus.
Wallinga, Alinde E.,, Eggen, B.J.L., Borght, Karin van der,, van der Zee, E.A, Wallinga, A.E., Luiten, P.G.M., Eggen, B.J.L.; id_orcid, Luiten, Paul G.M.,, Eggen, Bart J.L.,, Zee, Eddy A. van der,, van der Borght, K.   +10 more
core   +1 more source

Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E is an element of 4 status and cerebrospinal fluid amyloid-beta 42 levels [PDF]

, 2014
Introduction: Emerging evidence suggests that decreased adult hippocampal neurogenesis represents an early critical event in the course of Alzheimer's disease (AD).
Annas, Peter, Hans Basun, Basun, Hans, Keith A Wesnes, Edgar, Chris, Peter Annas, Wesnes, KA, Basun, H, Kaj Blennow, Blennow, K, Wesnes, Keith, Blennow, Kaj, Chris Edgar, Edgar, C, Annas, P,   +14 more
core   +1 more source

Altered intrinsic functional connectivity in language-related brain regions in association with verbal memory performance in euthymic bipolar patients [PDF]

, 2013
Potential abnormalities in the structure and function of the temporal lobes have been studied much less in bipolar disorder than in schizophrenia. This may not be justified because language-related symptoms, such as pressured speech and flight of ideas ...
David Linden, Viola Oertel-Knöchel, Britta Reinke, Reinke, Britta, Ven, Vincent van de, Vincent Ven, Oertel-Knöchel, Viola, Ven, Vincent, Linden, David, Vincent van de Ven, Silke Matura, David E. J. Linden, Matura, Silke, Linden, David E. J.   +13 more
core   +1 more source

Absent or low rate of adult neurogenesis in the hippocampus of bats (Chiroptera) [PDF]

, 2007
Bats are the only flying mammals and have well developed navigation abilities for 3D-space. Even bats with comparatively small home ranges cover much larger territories than rodents, and long-distance migration by some species is unique among small ...
Winter, Y, Amrein, Irmgard, Lipp Hans-Peter, Winter, Y., Lipp, Hans-Peter, Lipp, H P, Amrein Irmgard, Dechmann Dina K.N., Dechmann, D., Amrein, I, Hans-Peter Lipp, Amrein, I., Lipp, H., Winter, York, Dechmann, Dina K. N., Winter York, Irmgard Amrein, Dechmann, D K, Dina K N Dechmann, York Winter   +19 more
core   +2 more sources

Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy

American Journal of Medical Genetics Part A, Volume 197, Issue 8, August 2025.
ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore, Gianmichele Migaleddu, Pei‐Chien Tsai, Antonella Fogli, Maria Adelaide Caligo, Gabriele Siciliano, Mirco Cosottini, Yi‐Chung Lee, Yi‐Chu Liao, Michelangelo Mancuso, Roberto Ceravolo, Daniela Frosini   +11 more
wiley   +1 more source

Cholinergic system changes of falls and freezing of gait in Parkinson's disease

Annals of Neurology, Volume 85, Issue 4, Page 538-549, April 2019., 2019
Objective Postural instability and gait difficulties (PIGDs) represent debilitating disturbances in Parkinson's disease (PD). Past acetylcholinesterase positron emission tomography (PET) imaging studies implicate cholinergic changes as significant contributors to PIGD features.
Nicolaas I. Bohnen, Prabesh Kanel, Zhi Zhou, Robert A. Koeppe, Kirk A. Frey, William T. Dauer, Roger L. Albin, Martijn L.T.M. Müller   +7 more
wiley   +1 more source

From Big Data to the Clinic: Methodological and Statistical Enhancements to Implement the UK Biobank Imaging Framework in a Memory Clinic

Human Brain Mapping, Volume 46, Issue 3, February 15, 2025.
We optimised the UK Biobank imaging framework for memory clinic use by integrating enhanced quality control (QC) and supplementary analyses targeted towards dementia‐related changes. These analyses capture established and novel associations between brain metrics and dementia‐related phenotypes, creating a translational bridge between big data analytics
Grace Gillis, Gaurav Bhalerao, Jasmine Blane, Robert Mitchell, Pieter M. Pretorius, Celeste McCracken, Thomas E. Nichols, Stephen M. Smith, Karla L. Miller, Fidel Alfaro‐Almagro, Vanessa Raymont, Lola Martos, Clare E. Mackay, Ludovica Griffanti   +13 more
wiley   +1 more source

A Case of Parkinson’s Disease with No Lewy Body Pathology due to a Homozygous Exon Deletion in Parkin

Case Reports in Neurological Medicine, Volume 2018, Issue 1, 2018., 2018
Parkinson’s disease (PD) is a clinical diagnosis based on the presence of cardinal motor signs, good response to levodopa, and no other explanations of the syndrome. Earlier diagnostic criteria required autopsy for a definite diagnosis based on neuronal loss in the substantia nigra pars compacta (SNpc) and the presence of Lewy bodies and neurites. Here,
Krisztina Kunszt Johansen, Sverre Helge Torp, Matthew J. Farrer, Emil K. Gustavsson, Jan O. Aasly, Isabella Laura Simone   +5 more
wiley   +1 more source