Results 21 to 30 of about 6,565 (172)

Alternation of amplitude of low⁃frequency fluctuation and functional connectivity in the patients of Parkinson's disease with working memory impairment: a resting⁃state fMRI study

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To explore the characteristics of resting⁃state amplitude of low⁃frequency fluctuation (ALFF) and functional connectivity (FC) in patients with Parkinson's disease (PD) and working memory impairment, and to explore its correlation with ...
Wei⁃wen ZHANG, Peng CHEN, Man⁃li JIANG, Chi XIONG, Ying WANG, Chao⁃shi NIU   +5 more
doaj  

Use of diffusion spectrum imaging in preliminary longitudinal evaluation of amyotrophic lateral sclerosis: Development of an imaging biomarker [PDF]

, 2014
Previous diffusion tensor imaging (DTI) studies have shown white matter pathology in amyotrophic lateral sclerosis (ALS), predominantly in the motor pathways.
Abhinav, K, Chang, YF, El-Dokla, A, Fernandez-Miranda, JC, Ferrando, LM, Friedlander, RM, Lacomis, D, Yeh, FC   +7 more
core   +2 more sources

Morphological variations of the limbic-lobar border cortex on the inner side of human brain hemisphere [PDF]

, 2010
Background and Purpose: Medial side of brain hemispheres is divided into two cortical regions: the inner region – limbic, and the outer region – lobar one. As the limbic region is responsible for vegetative and sexual functions, memory and cognition, the
DU[AN ŠUŠČEVIĆ, GORAN SPASOJEVIĆ, SAŠA VUJNOVIĆ, SLOBODAN MALOBABIĆ, ZLATAN STOJANOVIĆ   +4 more
core   +1 more source

Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy

American Journal of Medical Genetics Part A, Volume 197, Issue 8, August 2025.
ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore, Gianmichele Migaleddu, Pei‐Chien Tsai, Antonella Fogli, Maria Adelaide Caligo, Gabriele Siciliano, Mirco Cosottini, Yi‐Chung Lee, Yi‐Chu Liao, Michelangelo Mancuso, Roberto Ceravolo, Daniela Frosini   +11 more
wiley   +1 more source

Cholinergic system changes of falls and freezing of gait in Parkinson's disease

Annals of Neurology, Volume 85, Issue 4, Page 538-549, April 2019., 2019
Objective Postural instability and gait difficulties (PIGDs) represent debilitating disturbances in Parkinson's disease (PD). Past acetylcholinesterase positron emission tomography (PET) imaging studies implicate cholinergic changes as significant contributors to PIGD features.
Nicolaas I. Bohnen, Prabesh Kanel, Zhi Zhou, Robert A. Koeppe, Kirk A. Frey, William T. Dauer, Roger L. Albin, Martijn L.T.M. Müller   +7 more
wiley   +1 more source

Vaskulaarne dementsus: uus algus [PDF]

, 2004
Kui 20. sajandi teisel poolel oli uurijate tulipunktiks Alzheimeri tõbi kui sagedasim dementsuse põhjus, siis praegu on vaskulaarne dementsus, eriti selle subkortikaalne vorm jällegi huviorbiidis ja hoopis uuest vaatenurgast.
Linnamägi, Ülla, Tomberg, Tiiu
core   +2 more sources

From Big Data to the Clinic: Methodological and Statistical Enhancements to Implement the UK Biobank Imaging Framework in a Memory Clinic

Human Brain Mapping, Volume 46, Issue 3, February 15, 2025.
We optimised the UK Biobank imaging framework for memory clinic use by integrating enhanced quality control (QC) and supplementary analyses targeted towards dementia‐related changes. These analyses capture established and novel associations between brain metrics and dementia‐related phenotypes, creating a translational bridge between big data analytics
Grace Gillis, Gaurav Bhalerao, Jasmine Blane, Robert Mitchell, Pieter M. Pretorius, Celeste McCracken, Thomas E. Nichols, Stephen M. Smith, Karla L. Miller, Fidel Alfaro‐Almagro, Vanessa Raymont, Lola Martos, Clare E. Mackay, Ludovica Griffanti   +13 more
wiley   +1 more source

A Case of Parkinson’s Disease with No Lewy Body Pathology due to a Homozygous Exon Deletion in Parkin

Case Reports in Neurological Medicine, Volume 2018, Issue 1, 2018., 2018
Parkinson’s disease (PD) is a clinical diagnosis based on the presence of cardinal motor signs, good response to levodopa, and no other explanations of the syndrome. Earlier diagnostic criteria required autopsy for a definite diagnosis based on neuronal loss in the substantia nigra pars compacta (SNpc) and the presence of Lewy bodies and neurites. Here,
Krisztina Kunszt Johansen, Sverre Helge Torp, Matthew J. Farrer, Emil K. Gustavsson, Jan O. Aasly, Isabella Laura Simone   +5 more
wiley   +1 more source

Atypical case of anterograde amnesia after cerebral infarction and anti-NMDA encephalitis post Covid 19 infection: A complex clinical case

European Psychiatry
Introduction Only a few cases of primary anterograde amnesia with confabulation after severe complex brain damage have been described in the literature.
M. Gebele
doaj   +1 more source

Alternations of Plasma Fatty Acids in Patients With Bipolar Depression Under Acute Treatment of rTMS Combined With Quetiapine and Mood Stabilizer

Brain and Behavior, Volume 15, Issue 2, February 2025.
Plasma fatty acids (FAs) were altered in patients with bipolar depression. Repetitive transcranial magnetic stimulation (rTMS) combined with quetiapine and mood stabilizer alleviated symptoms and changed plasma FAs composition in patients. We identified FAs panels, which can distinguish bipolar disorder (BD) from healthy control (HC), BD‐2w from HC ...
Huan Yu, Xue‐jun Liang, Yu‐ting Qiao, Lin Guo, Zhao‐yang Li, Cui‐hong Zhou, Wen‐jun Wu, Rui Li, Zheng‐wu Peng   +8 more
wiley   +1 more source