Virulence Factor Genes in Invasive Escherichia coli Are Associated with Clinical Outcomes and Disease Severity in Patients with Sepsis: A Prospective Observational Cohort Study [PDF]
Background: Escherichia coli harbours virulence factors that facilitate the development of bloodstream infections. Studies determining virulence factors in clinical isolates often have limited access to clinical data and lack associations with patient ...
Valentino D’Onofrio +4 more
doaj +2 more sources
Impact of Human Genetic Variation on C-Reactive Protein Concentrations and Acute Appendicitis [PDF]
BackgroundAcute appendicitis is one of the most common abdominal emergencies worldwide. Both environmental and genetic factors contribute to the disease. C-reactive protein (CRP) is an important biomarker in the diagnosis of acute appendicitis.
Isis Ricaño-Ponce +15 more
doaj +2 more sources
Evaluation of the compatibility from antibiotic use with the Gyssens plot in community acruired pneumonia patients in RSUP DR Wahidin Sudirohusodo [PDF]
Objectives: Pneumonia is the leading cause of morbidity and mortality worldwide, eighth rank in the United States. The use of antibiotic for pneumonia theraphy contribute the highest rate compared to the usage of antibiotic therapy for other diseases ...
Hasliyawati Hasan +2 more
doaj +2 more sources
Sepsis still becomes a major health problem worldwide, with a fairly high mortality rate ranging from 20 to 50%. Antibiotic therapy with rational use can reduce the mortality rate.
Mas Masyrifah +2 more
exaly +3 more sources
Evaluation and Comparison of Antibiotic Prescribing Practices and Treatment Outcomes in Children with Pneumonia Admitted to Public and Private Hospitals in Pakistan: A Retrospective Study [PDF]
Background Pneumonia remains a leading cause of mortality among children under five years worldwide, particularly in Pakistan. Aim This study aimed to evaluate antibiotic prescribing practices, diagnostic utilization, and treatment outcomes among ...
Ayesha Naseem +12 more
doaj +2 more sources
Qualitative evaluation of antimicrobial use with gyssens method in the internal medicine wards of Adam Malik General Hospital Medan [PDF]
Objective: Antimicrobial resistance will become one of the most lethal conditions, which will raise burdens in many sectors across the One Health spectrum.
Restuti Hidayani Saragih +9 more
doaj +2 more sources
Quantity and quality of antibiotic use in surgical and medical wards in a general academic hospital: A retrospective study [PDF]
Treatment of infectious diseases uses antibiotics to kill or inhibit the growth of pathogenic bacteria. Inappropriate antibiotic use triggers resistance, which in turn affects patient clinical outcomes, length of hospital stays, and treatment costs. This
Qibtiyah Mariyatul +8 more
doaj +2 more sources
Editorial: Antimicrobial Stewardship in Low- and Middle-Income Countries [PDF]
Inge C. Gyssens +2 more
doaj +2 more sources
Pneumonia is a respiratory infection that remains a public health problem and requires appropriate antibiotic therapy. However, irrational use of antibiotics has the potential to increase resistance and worsen patient clinical outcomes.
Nurul Chusna
exaly +3 more sources
Background: Many empirical antibiotics are prescribed unnecessarily, contributing to the rise in the incidence of antibiotic resistance. Preventing infection of surgical sites is one of the most frequent purposes of empirical antibiotic usage. Therefore,
Muhammad Hasan Bashari
exaly +3 more sources

