Teclistamab in Elderly Patients With Relapsed/Refractory Multiple Myeloma: A Subgroup Analysis of the French RetrosTECtive Cohort [PDF]
Introduction Real‐world data on teclistamab in relapsed or refractory multiple myeloma (R/R MM), particularly in elderly patients, remain limited. Methods We analysed efficacy and safety outcomes in patients ≥ 75 years from the French RetrosTECtive ...
A. Coste +26 more
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Outcome of patients with accelerated and blast‐phase myeloproliferative neoplasms not eligible for intensive chemotherapy or allogeneic hematopoietic cell transplantation treated by azacitidine alone or in combination—A FIM study [PDF]
Accelerated‐phase (AP) or blast‐phase (BP) myeloproliferative neoplasms (MPNs) are associated with dismal prognosis, with non‐curative therapies such as hypomethylating agents (HMAs) considered in patients not eligible for intensive therapy, while some ...
Corentin Orvain +32 more
doaj +2 more sources
Cerebellum/liver index on baseline 18F-FDG PET/CT to improve prognostication in post-transplant lymphoproliferative disorders: a multicenter retrospective study [PDF]
Background Besides International Prognostic Index (IPI) score, baseline prognostic factors of post-transplant lymphoproliferative disorders (PTLD) are poorly identified due to the rarity of the disease.
David Morland +19 more
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TLX1 translocation variants and enhancer hijacking influence clinical outcome in T‐cell acute lymphoblastic leukemia [PDF]
The T‐cell Leukemia Homeobox 1 (TLX1) oncogene is frequently deregulated in T‐cell acute lymphoblastic leukemia (T‐ALL) and T‐cell lymphoblastic lymphoma (T‐LBL).
Estelle Balducci +19 more
doaj +2 more sources
Epidemiological profile of constitutional thrombopathies in western Algeria [PDF]
Introduction. As with all rare or orphan diseases, the study of inherited platelet disorders should be multicentric to identify as many or as few patients as possible in a given region or country. The aim of our study is to evaluate the prevalence of
Réda Messaoudi +5 more
doaj +1 more source
Introduction. L’utilisation excessive des pesticides pose un véritable problème de santé publique, non seulement pour les personnes qui y sont exposées, mais aussi pour l’écosystème. Objectif.
Amal FEKI +4 more
doaj +1 more source
Preventive plasmapheresis for rituximab related flare in cryoglobulinemic vasculitis
Introduction: Rituximab monotherapy represents the main therapeutic option for cryoglobulinemic vasculitis (CV) with severe organ involvement. However, initial worsening of the CV, known as rituximab-associated CV flare (=CV flare), has been described ...
Léa Fornero +9 more
doaj +1 more source
Belantamab mafodotin (BM) is an anti-BCMA antibody-drug conjugate (GSK2857916) that represents an alternative option in multiple myeloma. We sought to assess the efficacy and safety of BM in a real-world setting in patients who benefited from an early ...
Alexis Talbot +49 more
doaj +1 more source
Debates on the role and timing of allogeneic hemtopoietic stem cell transplantation (HSCT) in acute myelogenous leukemia (AML) have persisted for decades.
Gerard Socie +23 more
doaj +1 more source
Introduction: Le paludisme est une érythropathie parasitaire due à des protozoaires du genre plasmodium. C'est de loin la parasitose qui touche le plus grand nombre de personnes et provoque le plus de décès . Le but de cette étude était de déterminer les
Mamady Diakite, et. al
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