Results 21 to 30 of about 2,778 (118)

Desregulación inmunológica y fisiopatología del consumo de alcohol y la enfermedad hepática alcohólica

open access: yesRevista de Gastroenterología de México, 2023
Resumen: La enfermedad hepática alcohólica (EHA) es una entidad clinicopatológica ocasionada por el consumo excesivo y crónico de alcohol. La enfermedad incluye un amplio espectro de anomalías celulares y tisulares que pueden causar daño agudo sobre ...
M. Martinez-Castillo   +9 more
doaj   +1 more source

Intrinsic cancer cell phosphoinositide 3‐kinase δ regulates fibrosis and vascular development in cholangiocarcinoma

open access: yesLiver International, Volume 43, Issue 12, Page 2776-2793, December 2023., 2023
Abstract Background & Aims The class I‐ phosphatidylinositol‐3 kinases (PI3Ks) signalling is dysregulated in almost all human cancers whereas the isoform‐specific roles remain poorly investigated. We reported that the isoform δ (PI3Kδ) regulated epithelial cell polarity and plasticity and recent developments have heightened its role in hepatocellular ...
Vanessa Bou Malham   +16 more
wiley   +1 more source

Immune dysregulation and pathophysiology of alcohol consumption and alcoholic liver disease

open access: yesRevista de Gastroenterología de México (English Edition), 2023
Alcoholic liver disease (ALD) is a clinical-pathologic entity caused by the chronic excessive consumption of alcohol. The disease includes a broad spectrum of anomalies at the cellular and tissual level that can cause acute-on-chronic (alcoholic ...
M. Martinez-Castillo   +9 more
doaj   +1 more source

Exploring the landscape of steatotic liver disease in the general US population

open access: yesLiver International, Volume 43, Issue 11, Page 2425-2433, November 2023., 2023
Abstract Background and Objective The aim of the present study is to explore the epidemiologic impact of the definition of steatotic liver disease (SLD) proposed by a multi‐society (American Association for the Study of the Liver‐the European Association for the Study of Liver Diseases‐Asociación Latinoamericana para el Estudio del Hígado) Delphi ...
Stefano Ciardullo   +3 more
wiley   +1 more source

C(spn)−X (n=1–3) Bond Activation by Palladium

open access: yesChemistry – A European Journal, Volume 28, Issue 26, May 6, 2022., 2022
Less is more! Our quantum chemical analyses reveal that the activity of palladium catalysts towards C−X bond activation increases along ethane, ethylene, acetylene because the steric repulsion between catalyst and substrate is relieved as the number of substituents around the carbon atom goes down.
Thomas Hansen   +6 more
wiley   +1 more source

Metallodrugs: an approach against invasion and metastasis in cancer treatment

open access: yesFEBS Open Bio, Volume 12, Issue 5, Page 880-899, May 2022., 2022
In this review, we examine the use of metallodrugs for cancer treatment, focussing on the advances in this type of therapy and the importance of these compounds, with emphasis on Pt, Ru, Au, Zn, and Cu as antimetastatic agents. In addition, we discuss the different mechanisms of action by which metallodrugs exert their therapeutic effects.
Mauricio M. González‐Ballesteros   +2 more
wiley   +1 more source

Utilización de injertos hepáticos de donantes cadavéricos: impacto de la implementación de un equipo local de valoración y procuración en México

open access: yesRevista de Gastroenterología de México, 2021
Resumen: Introducción y objetivos: La recuperación de injertos hepáticos de donante cadavérico en México es compleja. El objetivo de este manuscrito es presentar la experiencia en el uso de hígado durante el primer año de un equipo local de valoración y
D. Zamora-Valdés   +5 more
doaj   +1 more source

Development of a Hepatoprotective Herbal Drug from Turnera diffusa

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
The incidence of liver diseases, such as nonalcoholic fatty liver disease and drug‐induced liver injury, continues to rise and is one of the leading causes of acute hepatitis. Current trends suggest that these types of conditions will increase in the coming years.
Cecilia Delgado-Montemayor   +7 more
wiley   +1 more source

Eficacia de la rifaximina en los diferentes escenarios clínicos de la encefalopatía hepática

open access: yesRevista de Gastroenterología de México, 2020
Resumen: La encefalopatía hepática (EH) es una complicación frecuente en pacientes con cirrosis hepática y se asocia a una alta tasa de mortalidad.
C.E. Coronel-Castillo   +4 more
doaj   +1 more source

PROFILE OF PRO AND ANTI-INFLAMMATORY CYTOKINES IN PATIENTS WITH CHRONIC LIVER DISEASE IN THE COMPENSATION, INFLAMMATION AND IMMUNOSUPPRESSION PHASES

open access: yesAnnals of Hepatology, 2022
Introduction and objectives: Decompensated cirrhosis is defined by the onset of complications and is associated with immune dysfunction. This is the result of two processes: systemic inflammation and damage made by the immune system. Our objective was to
B. Tijerina-Soto   +4 more
doaj   +1 more source

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