Doubling measure and regularity to K-quasiminimizers of double-phase energy
We consider an integral functional involving the double-phase operator in a metric measure space equipped with a doubling measure. On the basis of suitable hypotheses on the function governing the phase changes, we design a unifying approach to establish
Cen Jinxia, Vetro Calogero, Zeng Shengda
doaj +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li +10 more
wiley +1 more source
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Harnack inequality for a class of functionals with non-standard growth via De Giorgi’s method
We study the regularity theory of quasi-minimizers of functionals with Lp(⋅)logL{L^{p(\,\cdot\,)}\log L}-growth. In particular, we prove the Harnack inequality and, in addition, the local boundedness and the Hölder continuity of the quasi-minimizers ...
Ok Jihoon
doaj +1 more source
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Boundedness and Hölder continuity of weak solutions of the nonlinear boundary-value problem for elliptic equations with general nonstandard growth conditions [PDF]
We study a nonlinear boundary-value problem for elliptic equations with critical growth conditions involving Lebesgue measurable functions. We prove global boundedness and Hölder continuity of weak solutions for this problem.
Gumpyong Ri, Dukman Ri
doaj +1 more source
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh +8 more
wiley +1 more source
Some properties of a kind of generalized Teodorescu operator in Clifford analysis
First, a kind of generalized Teodorescu operator which is related to the k-regular functions are defined. Then the boundedness and the Hölder continuity of the generalized Teodorescu operator are discussed.
Liping Wang
doaj +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source

