Results 261 to 270 of about 511,561 (316)

Enhanced in Vitro Immunogenicity of H-2 Antigens in the Presence of Ia Antigens

1976
In a primary and secondary MLC the in vitro immunogenicity of allogeneic PHA induced blast cells (which lack i region coded determinants) was compared to that of LPS imduced blast cells. Unlike LPS induced blast lymphocytes (stimulator cells) which induced high cytotoxic activity, PHA induced blast cells were found to be poor stimulator cells in a ...
H, Wagner, M, Röllinghoff
openaire   +2 more sources

Measurement of H-2 and Non-H-2 Antigens in the Mouse with the Footpad Swelling Test

The Journal of Immunology, 1976
Abstract The footpad swelling (FPS) test for delayed-type hypersensitivity in the mouse was evaluated for its ability to measure histocompatibility (H) antigens present on intact spleen cells or solubilized from a methylcholanthrene-(MCA) induced fibrosarcoma.
Kon, N D, Klein, P A
openaire   +2 more sources

Latent help to and from H‐2 antigens

European Journal of Immunology, 1992
AbstractAn optimized system for probing allo‐immunity to major histocompatibility complex (MHC) antigens by means of adoptive transfer is used to confirm and extend previous work showing that naturally occurring class I MHC antigens, while capable of inducing Th activity when presented in combination with other allo‐antigens, fail to do so on their own.
openaire   +2 more sources

Genetic Control by the H-2 Gene Complex of the Alloantibody Response to an H-2 Antigen

The Journal of Immunology, 1972
Abstract The genetic control of the immune response against an H-2 antigenic specificity was investigated. With the aid of five congenic mouse strains, B10.A, C57BL/10, B10.A(2R), B10.A(3R) and B10.A(5R), it was demonstrated that a genetic factor, possibly Ir-1, associated with the H-2(K) subdivision of the H-2b chromosome, exerts a ...
Stimpfling, J, Durham, T
openaire   +2 more sources

Analysis of the expression of H‐2 and H‐2‐linked antigens on mammary tumor cells

International Journal of Cancer, 1979
AbstractThe products of the recently discovered H‐2L locus were expressed on BALB/c mammary tumor cells and behaved as histocompatibility antigens, in contrast to the products of H‐2 linked loci (Qa‐loci) that did not influence the acceptance or rejection of tumor transplants.
Snoek, M, Demant, P
openaire   +2 more sources

H‐2 antigens on murine leukemia cells and viruses

International Journal of Cancer, 1972
AbstractElectron microscopic analysis of the distribution of H‐2 (b, d, k) antigens on the cell surface and viruses of Rauscher, Friend, Graffi, Mazurenko, Gross and SZ leukemia was carried out using the hybrid antibody test.H‐2 antigens occupied different areas on the surface of the cells, but their average content per 100 randomly selected cells ...
Dorfman, N, Stepina, V, Ievleva, E
openaire   +2 more sources

Teratocarcinoma transplantation antigens are encoded in the H-2 region

Immunogenetics, 1983
Evidence is presented for the existence of teratocarcinoma transplantation antigens (Gt) encoded within the H-2 complex and present also on adult tissues. It has not been possible to separate these Gt loci from H-2 by recombination, and Gt factors map to each end of the H-2 complex.
Johnson, L L, Clipson, L J, Dove, W F, Feilbach, J, Maher, J, Shedlovsky, A   +5 more
openaire   +2 more sources

Antibody‐induced changes in expression of the H‐2 antigen

European Journal of Immunology, 1974
AbstractContinuous exposure of a BALB/c myeloma line to anti‐H‐2d antibody in the absence of complement, for 3 hours at 37 °C, results in the loss of sensitivity to lysis by added complement or by added anti‐H‐2d and complement (antigenic modulation). 125I‐labeled anti‐H‐2d was used to follow the fate of the modulating antibody.
Lesley, J, Hyman, R
openaire   +2 more sources

Detection of H-2 and sendai virus antigens by chemiluminescence

Journal of Immunological Methods, 1981
Two monoclonal antibodies reacting with Ia9 and H2.2, respectively, have been added to spleen cell suspensions prepared from mice of different H-2 haplotypes. Cellular light emission was monitored in a liquid scintillation spectrometer operated in the out-of-coincidence mode.
E, Peterhans, H, Albrecht, R, Wyler
openaire   +2 more sources

THE PRESENCE OF NON-H-2 HISTOCOMPATABILITY SPECIFICITIES IN PREPARATIONS OF MOUSE H-2 ANTIGENS

Transplantation, 1963
SUMMARY Preparations of mouse H-2 histocompatibility antigens, isolated by following haemagglutination inhibitory activity, have been examined for the presence of antigeneic specificities determined by other histocompatibility loci (non H-2 antigens).
openaire   +2 more sources