Results 121 to 130 of about 12,133,437 (297)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Traffic data collection using a bridge-weigh-in-motion system in a cable-stayed bridge

, 2017
Reliable live traffic data collection is crucial for effective pavement life prediction, fatigue estimation, vibration control, maintenance, and condition assessment of the bridge structures.
Samali, Bijan (R17646), Kalhor, Hamed, Zhu, Xinqun (R14089), Alamdari, Mehrisadat M.   +3 more
core  

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Simulation and Comparison of Twenty Five Level Diode Clamped & Cascaded H-Bridge Multilevel Inverter

Iranian Journal of Electrical and Electronic Engineering, 2018
This paper presents the comparative study of three phase twenty five level diode clamped and cascaded H-bridge multilevel inverters. The comparison is made in respect of requirement of devices, quality of output voltage and reduction of total harmonic ...
S. R. Sadu, P. V. Prasad, G. N. Srinivas
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Determination of safe speeds for a coach travelling on a floating bridge

Transportation Research Interdisciplinary Perspectives
Coastal highway route E39 is immense road project in Norway with the aim to shorten the journey time between the south part (Kristiansand city) and the north part of the country (Trondheim city).
Dragan Sekulic, Alexey Vdovin, Bengt Jacobson, Simone Sebben, Stian Moe Johannesen   +4 more
doaj   +1 more source

Piezoelectric Energy Harvesting Controlled with an IGBT H-Bridge and Bidirectional Buck-Boost for Low-Cost 4G Devices. [PDF]

Sensors (Basel), 2020
Teso-Fz-Betoño D, Aramendia I, Martinez-Rico J, Fernandez-Gamiz U, Zulueta E.   +4 more
europepmc   +1 more source

The proposed Australasian composite bridge standard, AS/NZS 5100 Part 6, Steel and composite construction

, 2013
This paper details the ongoing progress by the Australian Standards Committee BD-90-06 on the Australasian Standard for Bridge Design, Steel and Composite Construction, AS/NZS 5 100 Part 6 which is currently being prepared for public comment and is ...
Uy, Brian, Kang, Won-Hee (R16823), Hicks, Stephen   +2 more
core  

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source