Results 111 to 120 of about 1,831,004 (275)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The h-index is probably the more popular method of evaluation of the impact of academic research-ers, and several modifications, related indexes or criticisms have been proposed. Also, h-indexes should only be compared for researchers in a same research field, but it is frequently used for com-paring researchers in different fields, greatly in private ...
openaire +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Design of Deep Learning-Based Pressure Injury Stage Classification Device
Pressure injury or pressure ulcers could occur due to continuous pressure on the bony prominence of the skin and tissue. Geriatric patients, especially those with limited mobility and several comorbidities, are more susceptible to pressure injury.
Wahmisari Priharti +4 more
doaj +1 more source
The H Index Myth: A Form of Fanaticism or a Simple Misconception? [PDF]
Quaia E, Vernuccio F.
europepmc +1 more source
Commenting article http://arxiv.org/abs/1108.3901 by Ludo Waltman and Nees Jan van Neck on "The inconsistency of the h-index"
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Comparative Analysis of YOLOv8 and HSV Methods for Traffic Density Measurement
Traffic density measurement is a critical component in traffic management and urban planning. This study addresses the challenge of accurately measuring traffic density by comparing the performance of the YOLOv8 segmentation method with the traditional ...
Prof. I Gede Pasek Suta Wijaya +2 more
doaj +1 more source
Measuring h-index and scholarly productivity in academic dermatology in Canada. [PDF]
Azar M +13 more
europepmc +1 more source

