Results 201 to 210 of about 19,217,453 (333)

Reduction of edge-localized mode intensity using high-repetition-rate pellet injection in tokamak H-mode plasmas.

Physical Review Letters, 2013
L. Baylor, N. Commaux, T. Jernigan, S. Meitner, S. Combs, R. Isler, E. Unterberg, N. Brooks, T. Evans, A. Leonard, T. Osborne, Paul Parks, E. Strait, M. Fenstermacher, C. Lasnier, R. Moyer, A. Loarte   +16 more
semanticscholar   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Dual-mode 0D/2D spatial asymmetry optoelectronic device enabled by in situ microzone femtosecond laser deposition. [PDF]

Light Sci Appl
Li Z, Zou G, Huo J, Peng J, Sun T, Xiao Y, Huo J, Feng B, Liu L.   +8 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Design, green synthesis and biological evaluation of fluorinated <i>N</i>-acyl sulfonamides as novel anti-inflammatory agents: an <i>in vivo</i> and <i>in silico</i> study. [PDF]

RSC Adv
Litim Z, Ben Abdeljaoued A, Abdelhamid A, Bouraoui A, Özdemir İ, Hamdi N, Soussi MA, Kraiem J.   +7 more
europepmc   +1 more source

Measurements of the H-mode pedestal region on Alcator C-Mod [PDF]

, 1997
Boivin, R.L., Granetz, R.S., Greenwald, M., Hubbard, A.E., Hutchinson, I.H., In, J., Irby, J.H., Kesner, B., Labombard, B., Lin, Y., Pedersen, T.S., Rice, J.E., Snipes, J.A., Stek, P.C., Takase, Y., Wolfe, S.M., Wukitch, S.   +16 more
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Integrating Three Functional Subsets of T Cell Immunity Into an Integrative Model for Cancer Immunotherapy. [PDF]

Immune Netw
Park J, Ryu H.
europepmc   +1 more source

Role of zonal flow predator-prey oscillations in triggering the transition to H-mode confinement.

Physical Review Letters, 2012
L. Schmitz, L. Zeng, T. Rhodes, J. Hillesheim, E. Doyle, R. Groebner, W. Peebles, K. Burrell, G. Wang   +8 more
semanticscholar   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source