Results 51 to 60 of about 1,276,201 (259)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Poloidal structure of the edge parallel flow in H-mode, L-mode and I-mode confinement regimes

Nuclear Fusion
Impurity profiles have been measured with the edge high field side (HFS) and low field side (LFS) charge exchange recombination spectroscopy suite at ASDEX Upgrade enabling the study of the poloidal structure of the edge parallel flow in H-mode, L-mode ...
D.J. Cruz-Zabala, E. Viezzer, P. Cano-Megias, M. Cavedon, R. Dux, U. Plank, T. Pütterich, K. McKay, A. Rodriguez-Gonzalez, M. Garcia-Munoz, the ASDEX Upgrade Team   +10 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Nonlinear simulations of the peeling-ballooning instability of super H-modes in the HL-3 tokamak

Nuclear Fusion
As the newly built tokamak in China, HL-3 will explore high-performance operation scenarios, such as super H-mode. The energy confinement and core parameters in the super H-mode can be much larger than that in the normal H-mode.
Yiren Zhu, Wulyu Zhong, Xiaolan Zou, Jiaxian Li, Miao Xue, Zhengji Li, Lei Xue, Guoliang Xiao, Ruihai Tong, Yunpeng Zou, Jiao Yin, Anshu Liang, Linzi Liu, Boda Yuan, Min Xu, HL-3 Team   +15 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

H_∞ Sliding Mode Control: A Recent Review of Applications and Design Methods

IEEE Access
The $H_{\infty }$ Sliding Mode Control ( $H_{\infty }$ SMC) approach was introduced at the onset of this millennium as a proficient strategy integrating sliding mode and $H_{\infty }$ control principles to leverage their robust attributes while ...
Ali H. Mhmood, Muhammad Nasiruddin Mahyuddin   +1 more
doaj   +1 more source

H.264 SVC Complexity Reduction Based on Likelihood Mode Decision

The Scientific World Journal, 2015
H.264 Advanced Video Coding (AVC) was prolonged to Scalable Video Coding (SVC). SVC executes in different electronics gadgets such as personal computer, HDTV, SDTV, IPTV, and full-HDTV in which user demands various scaling of the same content.
L. Balaji, K. K. Thyagharajan
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Phenomenological model for H-mode [PDF]

, 1985
A phenomenological model has been developed to clarify the role of the boundary configuration in the heat transport of the H-mode regime. We assume that the dominant mechanism of heat loss at the edge of the plasma is convection and that the diffusion coefficient (D/sub edge/) at the edge of the plasma increases rapidly with plasma pressure, but drops ...
openaire   +2 more sources