Results 91 to 100 of about 884,903 (262)

ewN2HDECAY - A program for the Calculation of Electroweak One-Loop Corrections to Higgs Decays in the Next-to-Minimal Two-Higgs-Doublet Model Including State-of-the-Art QCD Corrections

, 2019
We present in this paper our new program package ewN2HDECAY for the calculation of the partial decay widths and branching ratios of the Higgs bosons of the Next-to-Minimal 2-Higgs Doublet Model (N2HDM).
Krause, M., Mühlleitner, M.
core   +1 more source

A Mass Spectrometry Approach Reveals Fatty Acid Isomerism in Tomato Cold Tolerance

Advanced Science, EarlyView.
An enhanced mass spectrometry approach reveals fatty acids (FAs) and FA isomers that are critical for tomato cold tolerance. Applying specific FA isomers can partially rescue cold sensitivity in tomato mutant plants, highlighting the importance of FA isomers in plant cold stress adaptation.
Leelyn Chong, Hengxue Shi, Qirui Yu, Xiaoning Shi, Zhaoxing Jia, Ziyun Dong, Yu Xia, Yingfang Zhu   +7 more
wiley   +1 more source

Lithium Exposure Causes Trophoblast Cuproptosis by Upregulating FOXO1/STEAP4 Axis in Unexplained Miscarriage

Advanced Science, EarlyView.
Li exposure up‐regulates FOXO1 expression levels and thus promotes FOXO1‐mediated STEAP4 transcription, up‐regulating STEAP4 levels. Subsequently, STEAP4 up‐regulates intracellular Cu+ ion levels and causes cuproptosis, which further induces miscarriage.
Shuaishuai Xing, Yanbing Lin, Yi Sun, Xiaoping Yue, Qigang Fan, Jisheng Nie, Zhihong Zhang, Yajing Liu, Juntang Yang, Qingzheng Kang, Yanxin Wang, Haijun Yan, Chan Tian, Ying Chang, Huidong Zhang   +14 more
wiley   +1 more source

Pathogenicity of Mediator Complex Subunit 27 (MED27) in a Neurodevelopmental Disorder with Cerebellar Atrophy

Advanced Science, EarlyView.
MED27 is one of the 26 subunits in the human Mediator complex (MED). Neurodevelopmental disorder‐causing MED27 genetic variants induce instability of MED, leading to disrupted DNA occupancy, altered chromatin interaction, and subsequent transcriptional dysregulation of critical downstream genes, including master regulatory transcription factors ...
Nuermila Yiliyaer, Xiaocheng Li, Tianyu Guo, Haiying Zhou, Lihai Gong, Luowei Yuan, Yang Fu, Yulong Qiao, Ying Lam Lui, Nuo Chen, Pengfei Lin, Hoi Hung Cheung, Ho Ko, Linyan Meng, Xiao Chen, Yong Lei, Kin Ming Kwan, Huating Wang, Shen Gu   +18 more
wiley   +1 more source

Photoionization Modeling of the Low Luminosity Seyfert 1 Nucleus in NGC 3516

, 2015
Spectroscopic observations of the low luminosity Seyfert 1 nucleus in NGC 3516 obtained with the Hubble Space Telescope show that the visible spectrum is dominated by the Balmer emission lines of Hydrogen (H) and a continuum luminosity that rises into ...
Devereux, Nick
core   +1 more source

MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

Advanced Science, EarlyView.
Herbal medicine, with its multicomponent and multitarget potential, is often studied primarily for traditional forms, especially phytochemicals. Currently, ulcerative colitis lacks natural, low‐toxicity therapies, yet emerging research highlights plant‐derived exosomes as a promising option.
Ruipeng Shi, Wen Tan, Haochun Jin, Sio I Chan, Wei Li, Si San Lei, Guozhen Cui, Yitao Wang, Dong‐Hua Yang, Zhangfeng Zhong   +9 more
wiley   +1 more source

T2T Genomes Unveil Centromere Architecture and Adaptive Divergence in Large Yellow Croaker (Larimichthys crocea)

Advanced Science, EarlyView.
This study presents telomere‐to‐telomere genome assemblies for two populations of Larimichthys crocea. We identified centromere‐specific tandem repeats invaded by LTR/ERV1 retrotransposons, unique 5S rRNA enrichment patterns, and population‐specific structural variants. Comparative genomic analyses further reveal distinct adaptive mechanisms in the MYD
Yu Cui, Yingbo Yuan, Bi Wang, Baolan Wu, Mingyi Cai, Ming Fang, Weiliang Shen, Xiongfei Wu, Fang Han, Zhiyong Wang   +9 more
wiley   +1 more source

Iron Single‐Atom Catalyzed N‐Alkylation of Amines with Alcohols via Solvent‐Free Borrowing Hydrogen Strategy

Advanced Science, EarlyView.
An innovative iron‐based single‐atom catalyst (FeSA@N‐G) with Fe1–N4 coordination is presented, synthesized through a simple and scalable method. It exhibits exceptional activity and selectivity in N‐alkylation via the borrowing hydrogen strategy under solvent‐free conditions, producing water as the only by‐product. Achieving record TOF (413.1 h-1) and
Arun D. Kute, Hanumant B. Kale, Priti Sharma, Srinivasu Kancharlapalli, Gajanan Y. Shinde, Ruchi Chauhan, Ajay K. Singh, Shan Jiang, Jeffrey T. Miller, Radek Zboril, Yifeng Wang, Manoj B. Gawande   +11 more
wiley   +1 more source

Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization

Advanced Science, EarlyView.
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay, Hadeeqa G. Raza, Richard G. Doveston, Aneika C. Leney   +3 more
wiley   +1 more source

Material‐to‐Application Integration: Rapid Fabrication of Field‐Deployable Hydrogel‐SiO2 DNA Separator for Low‐Resource Point‐of‐Care Diagnostics

Advanced Science, EarlyView.
A rapidly fabricated hydrogel‐SiO2 composite enables ultralow‐cost, equipment‐minimized DNA extraction, outperforming commercial kits. Hierarchical microstructures enhance hydrophobic/salt‐bridge‐driven adsorption. Integrated with visual LAMP, this field‐deployable system detects Vibrio parahaemolyticus at 10 CFU mL−1 in <40 min, offering ...
Peipei Li, Xinrong Li, Haojie Wu, Dongmei Yue, Yubo Shang, Shan Gao, Bai Wang, Xiaobin Jiang, Jingwei Jiang, Zunchun Zhou   +9 more
wiley   +1 more source