Results 31 to 40 of about 317,019 (228)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Reduction of Influenza A Virus Prevalence in Pigs at Weaning After Using Custom-Made Influenza Vaccines in the Breeding Herds of an Integrated Swine Farm System

Viruses
Vaccination is a common influenza A virus (IAV) control strategy for pigs. Vaccine efficacy depends on strain cross-protection and effective vaccination program implementation.
Jorge Garrido-Mantilla, Juan Sanhueza, Julio Alvarez, Jeremy S. Pittman, Peter Davies, Montserrat Torremorell, Marie R. Culhane   +6 more
doaj   +1 more source

The Differences Between the Model and Competencies of the Strategic Partnership Between Human Resource Management and Line Managers in National and Multinational Companies

Internext: Revista Eletrônica de Negócios Internacionais, 2018
The aim of this article is to compare the characteristics of the partnering model between the human resource management (HRM) area and line managers (LM) in national and multinational companies, highlighting significant differences, in particular those ...
Junia Botter, Denise Gonçalves Rosa, Luciana Campos Lima   +2 more
doaj   +1 more source

Rotavirus surveillance in Kisangani, the Democratic Republic of the Congo, reveals a high number of unusual genotypes and gene segments of animal origin in non-vaccinated symptomatic children. [PDF]

PLoS ONE, 2014
Group A rotavirus (RVA) infections form a major public health problem, especially in low-income countries like the Democratic Republic of the Congo (COD).
Elisabeth Heylen, Bibi Batoko Likele, Mark Zeller, Stijn Stevens, Sarah De Coster, Nádia Conceição-Neto, Christel Van Geet, Jan Jacobs, Dauly Ngbonda, Marc Van Ranst, Jelle Matthijnssens   +10 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Analysis of factors influencing community's role in efforts to prevent DHF in Tinalan Village Kediri city

Journal of Nursing Practice
Latar Belakang : Minimnya partisipasi masyarakat dalam upaya pencegahan penyakit DBD dikarenakan kurangnya dukungan dari petugas kesehatan, tokoh masyarakat dan motivasi masyarakat dalam memutus mata rantai penularan DBD.
Maria Nubatonis, Indasah, Rahmania Ambarika   +2 more
doaj   +1 more source

Immunogenicity of Three Different Influenza Vaccines against Homologous and Heterologous Strains in Nursing Home Elderly Residents

Clinical and Developmental Immunology, 2010
We studied whether MF59-adjuvanted influenza vaccine improves immunity against drifted influenza strains in institutionalised elderly with underling chronic health conditions.
Vincenzo Baldo, Tatjana Baldovin, Michele Pellegrini, Gabriele Angiolelli, Silvia Majori, Annarosa Floreani, Marta Cecilia Busana, Chiara Bertoncello, Renzo Trivello   +8 more
doaj   +1 more source

Charm and beauty structure of the proton [PDF]

, 2006
This paper will review the data collected by the H1 and ZEUS Collaborations concerning the production of heavy quarks (charm and beauty) at the electron-proton collider HERA.
Brugnera, R.
core   +1 more source

Experimental review of diffractive phenomena

, 2004
A review is given of the measurements of the hard diffractive interactions in recent years from two high-energy colliders, the HERA $ep$ collider and the Tevatron $p\bar{p}$ collider.
Abbott, Abe, Affolder, Affolder, Chekanov, Chekanov, Collins, Collins, L. Favart   +8 more
core   +2 more sources

Dynamical Parton Distributions of the Nucleon up to NNLO of QCD [PDF]

, 2008
A new generation of (unpolarized) dynamical parton distribution functions of the nucleon is determined. After introducing basic elements of perturbative QCD, the dynamical model is discussed and compared with the approach to parton distributions used by ...
Adloff, Adloff, Atkas, Breitweg, Chekanov, Chekanov, Gluck, Glück, Glück, Glück, Glück, Glück, Glück, Halzen, Lai, Lastovicka, Lobodzinska, Martin, Martin, Martin, P. Jimenez-Delgado, Pumplin, Pumplin, Tung, Vogt   +24 more
core   +2 more sources