Results 81 to 90 of about 302,853 (230)

Factores pronóstico asociados a la duración de la urticaria espontánea crónica en pacientes que acuden al Servicio de Alergología Clínica IPS Universitaria – Universidad de Antioquia

Iatreia, 2013
INTRODUCCIÓN: no existen hasta la fecha marcadores clínicos o de laboratorio que permitan predecir la duración de la urticaria, con resultados reproducibles en los diferentes estudios realizados.
Sara Elizabeth Sus Carrizosa, María Nelly Restrepo Colorado, Liliana Tamayo Quijano, Ricardo Cardona Villa   +3 more
doaj  

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Horseshoe-based Bayesian nonparametric estimation of effective population size trajectories

, 2019
Phylodynamics is an area of population genetics that uses genetic sequence data to estimate past population dynamics. Modern state-of-the-art Bayesian nonparametric methods for recovering population size trajectories of unknown form use either change ...
Carpenter B., Easton N.A., Felsenstein J., Holmes C.E., Murray I., Neal R., Palacios J.A., R Core Team, Watanabe S.   +8 more
core   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

PENGEMBANGAN MULTIMEDIA PEMBELAJARAN INTERAKTIF DENGAN MODEL LUTHER DALAM MATA PELAJARAN IPS PADA SISWA KELAS VIII SEMESTER GENAP TAHUN PELAJARAN 2013/2014 DI SMP NEGERI 5 NEGARA

Jurnal Edutech Undiksha, 2015
Sampai saat ini hasil belajar IPS pada siswa kelas VIII di SMP Negeri 5 Negara belum memuaskan. Salah satu indikasinya adalah capaian rerata hasil belajar IPS sebesar 67 yang masih di bawah angka nilai Kriteria Ketuntasan Minimal (KKM) nasional yang ...
Ni Kadek Tina Pirgayanti ., Prof. Dr. Anak Agung Gede Agung,M.Pd ., Luh Putu Putrini Mahadewi, S.Pd .   +2 more
doaj   +1 more source

ewN2HDECAY - A program for the Calculation of Electroweak One-Loop Corrections to Higgs Decays in the Next-to-Minimal Two-Higgs-Doublet Model Including State-of-the-Art QCD Corrections

, 2019
We present in this paper our new program package ewN2HDECAY for the calculation of the partial decay widths and branching ratios of the Higgs bosons of the Next-to-Minimal 2-Higgs Doublet Model (N2HDM).
Krause, M., Mühlleitner, M.
core   +1 more source

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

Advanced Science, EarlyView.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu, Bingxing An, Jumei Zheng, Qiao Wang, Zhirui Yang, Zhengda Li, Dawei Liu, Fan Ying, Jie Wen, Lingzhao Fang, Guiping Zhao   +10 more
wiley   +1 more source

MARCO+ Tumor‐Associated Macrophages Impede CD8+ T Cell Immunity to Facilitate Immunotherapy Resistance in Renal Cell Carcinoma

Advanced Science, EarlyView.
MARCO+ TAMs dominate restrained cytotoxicity of CD8+ CTLs and ICB resistance in RCC. Mechanically, MARCO impairs MHC‐I‐mediated neoantigen cross‐presentation via the SOCS1‐JAK1‐STAT1‐NLRC5 signaling cascade in TAMs. Targeted MARCO treatment boosts macrophage antigen cross‐presentation and empowers CD8+ T cells, thereby potentiating ICB efficacy ...
Jiayuan Chen, Jiazhi Mo, Jinchang Wei, Mengnan Qu, Jie Dai, Yan Kong, Huayan Xu, Juan Li, Xieqiao Yan, Chuanliang Cui, Lu Si, Zhihong Chi, Jun Guo, Xiaowen Wu, Xinan Sheng   +14 more
wiley   +1 more source

Photoionization Modeling of the Low Luminosity Seyfert 1 Nucleus in NGC 3516

, 2015
Spectroscopic observations of the low luminosity Seyfert 1 nucleus in NGC 3516 obtained with the Hubble Space Telescope show that the visible spectrum is dominated by the Balmer emission lines of Hydrogen (H) and a continuum luminosity that rises into ...
Devereux, Nick
core   +1 more source

A Hexadecacationic Metal–Organic Cage for Anchoring Sulfonates: High‐Order Binding of Di‐ and Trisulfonates and High‐Performance Removal of Perfluorosulfonates from Water

Advanced Science, EarlyView.
Developing synthetic hosts that can bind sulfonate anions or sequester perfluorosulfonates is crucial in biological and environmental sciences. Here, a Zr‐based metal–organic cage (1) integrating electron‐deficient tripyridinium panels is designed and synthesized.
Yawei Liu, Gen Li, Xiang Zhang, Zelin Du, Tingting Zhang, Yongya Zhang, Roy Lavendomme, En‐Qing Gao, Dawei Zhang   +8 more
wiley   +1 more source