Results 101 to 110 of about 1,949,573 (273)

A New High Energy Photon Tagger for the H1 - Detector at HERA [PDF]

, 2000
The H1 detector at HERA has been upgraded by the addition of a new electromagnetic calorimeter. This is installed in the HERA tunnel close to the electron beam line at a position 8m from the interaction point in the electron beam direction.
Andreev, V. F., Belousov, A. S., Fomenko, A. M., Gorbov, L. A., Greenshaw, T., Levonian, S. V., Malinovski, E. I., Maxfield, S. J., Sheviakov, I. P., Smirnov, P. A., Soloviev, Yu. V., Winter, G. -G.   +11 more
core   +1 more source

Tunable Applicator for Microneedle‐Based Medical Devices

Advanced Materials Technologies, EarlyView.
This paper presents a simple, low‐cost tunable applicator (TAPP) for microneedle array patches that uses a material‐agnostic controlled‐fracture mechanism to ensure reliable skin penetration and uniform array engagement. The scalable, modular design is compatible with injection molding and 3D printing, can be integrated directly into patches, and is ...
Dan Ilyn, Jihyun (Luna) Hwang, Ian A. Coates, Jacob Dobson, Andy H. Hung, Netra U. Kamat, John R. Tumbleston, Maria T. Dulay, Gunilla B. Jacobson, Joseph M. DeSimone   +9 more
wiley   +1 more source

Molecular Appendix Adjusted Architectural Propagations of Red‐Light Controlled Macroscopic Photoactuating Performances

Advanced Robotics Research, EarlyView.
Amphiphilic chloroazobenzenes, bearing different amino acids as end groups alanine, phenylalanine, and valine, exhibit excellent photoisomerizations. Varying structures of three amino acid groups participate in supramolecular formations and therefore photoinduced morphological transformations via adjusting intermolecular interactions. These interaction
Shuangshuang Meng, Ming‐Hin Chau, Takashi Kajitani, Franco King‐Chi Leung   +3 more
wiley   +1 more source

Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons

Advanced Science, EarlyView.
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen‐xia Tian, Longlong Si   +14 more
wiley   +1 more source

Construction and Expression of nm23-H1 Gene with Different Enzyme Activities and Resistant Specific shRNA in Eukaryotic Expression Vector

Chinese Journal of Lung Cancer, 2014
Background and objective It has been proven that nm23-H1 gene was a tumor metastatic suppressor gene. However, it’s molecular mechanism of suppressing metastasis remains unexplored.
Zhansheng LU, Lili GUO, Lin LI, Zhihao WU, Qinghua ZHOU   +4 more
doaj   +1 more source

*h3 > h1, *h2 > h1 eta horiei datxezkien zenbait fenomenoz [PDF]

Lapurdum, 2009
The etymological value of / h / in Basque, especially when occurring in initial position, has been widely debated. Here we try to show that there are many instances of h- (not only in borrowings but also in patrimonial vocabulary) that have not been arbitrarily added in that position but they have moved there from intervocalic -n- (sometimes on the ...
openaire   +2 more sources

Redefining Dendritic Cell Vaccines: Synergistically Co‐priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines

Advanced Science, EarlyView.
Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu, Xianlan Chen, Jin Wang, Yuhan Liu, Sidra Mustafa, Lu Diao, Rongrong Zhao, Haiyang Chi, Kang Hu, Jiashan Zhu, Jun Zhao, Mi Liu   +11 more
wiley   +1 more source

Humanized VHH-hFc Fusion Proteins Targeting the L-HN Fragment of Tetanus Toxin Provided Protection In Vivo

Antibodies
Background: Tetanus toxin, produced by Clostridium tetani, is the second deadliest known toxin. Antibodies capable of neutralizing tetanus toxin (TeNT) are vital for preventing and treating tetanus disease.
Yating Li, Kexuan Cheng, Jiazheng Guo, Yujia Jiang, Qinglin Kang, Rong Wang, Peng Du, Chen Gao, Yunzhou Yu, Zhixin Yang, Wei Wang, Jiansheng Lu   +11 more
doaj   +1 more source

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source