Swine Influenza Virus Antibodies in Humans, Western Europe, 2009
Serologic studies for swine influenza viruses (SIVs) in humans with occupational exposure to swine have been reported from the Americas but not from Europe.
Nancy A. Gerloff +8 more
doaj +1 more source
Cross-protection against European swine influenza viruses in the context of infection immunity against the 2009 pandemic H1N1 virus : studies in the pig model of influenza [PDF]
Pigs are natural hosts for the same influenza virus subtypes as humans and are a valuable model for cross-protection studies with influenza. In this study, we have used the pig model to examine the extent of virological protection between a) the 2009 ...
A Krumbholz +58 more
core +6 more sources
A systematic review of reported reassortant viral lineages of influenza A [PDF]
BACKGROUND: Most previous evolutionary studies of influenza A have focussed on genetic drift, or reassortment of specific gene segments, hosts or subtypes.
Ferguson, NM +3 more
core +2 more sources
: Influenza A is a viral respiratory tract disease, which is transmitted on a large scale by the Myxovirus influenzae virus, through person-to-person contact by dissemination of droplets containing viral particles.
Ellen Karollyne Santos Lopes +5 more
doaj +1 more source
Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus [PDF]
Aim: The only small molecule drugs currently available for treatment of influenza A virus (IAV) are M2 ion channel blockers and sialidase inhibitors. The prototype thiazolide, nitazoxanide, has successfully completed Phase III clinical trials against ...
Andrew V Stachulski +17 more
core +1 more source
Exploring the interaction of influenza A subtypes H1N1 and H3N2 based on an evolution-driven transmission model [PDF]
Abstract Two influenza A subtypes (H1N1 and H3N2) co-circulate and pose a serious disease burden globally. It is unclear about the extent of cross protection between these two influenza A subtypes as well as the impact of cross protection on influenza dynamics.
Gang Wang +6 more
openaire +1 more source
Influenza research database: an integrated bioinformatics resource for influenza research and surveillance. [PDF]
BackgroundThe recent emergence of the 2009 pandemic influenza A/H1N1 virus has highlighted the value of free and open access to influenza virus genome sequence data integrated with information about other important virus characteristics.DesignThe ...
Baumgarth, Nicole +16 more
core +1 more source
Structural and Functional Analysis of NS1 and NS2 Proteins of H1N1 Subtype
Abstract Influenza A virus (H1N1), a genetic reassortment of endemic strains of human, avian and swine flu, has crossed species barrier to human and apparently acquired the capability of human to human transmission. Some strains of H5N1 subtype are highly virulent because NS1 protein inhibits antiviral interferon α/β production.
Parveen Salahuddin, Asad U. Khan
openaire +2 more sources
Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine [PDF]
Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine ...
A. L. Vincent +58 more
core +1 more source
Efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the classical swine H1N1 subtype influenza virus in mice and pigs [PDF]
Swine influenza (SI) is an acute, highly contagious respiratory disease caused by swine influenza A viruses (SwIVs), and it poses a potential global threat to human health. Classical H1N1 (cH1N1) SwIVs are still circulating and remain the predominant subtype in the swine population in China.
Feng Wen +7 more
openalex +4 more sources

