Results 71 to 80 of about 14,697 (220)

Function within disorder: Small heat shock proteins use different functional regions to chaperone tau aggregation

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract In numerous neurodegenerative diseases known collectively as tauopathies, the microtubule‐associated protein tau forms fibrillar aggregates that are hallmarks of disease pathology. Tauopathies represent a substantial fraction of diseases associated with protein misfolding.
Mia Cervantes   +5 more
wiley   +1 more source

A Retrospective Descriptive Analysis of Consultations Provided by the National Poisons Centre Relating to Medicines on the Aotearoa New Zealand Antidote Stocking Guideline, 2020–2025

open access: yesEmergency Medicine Australasia, Volume 38, Issue 5, October 2026.
ABSTRACT Objective Many antidotes are relatively rare‐use, indication‐specific medicines with a variable evidence base. In Aotearoa New Zealand, there are no national statistics available on their use. This study aimed to characterize the numbers of cases and advice provided by the Aotearoa New Zealand National Poisons Centre (NZNPC) on the use of true
Eeva‐Katri Kumpula, William Boroughf
wiley   +1 more source

Upscaling Genotyping by Amplicon Sequencing With GBAS‐GUI

open access: yesMolecular Ecology Resources, Volume 26, Issue 7, October 2026.
ABSTRACT Genotyping by amplicon sequencing (GBAS) is a relatively low‐cost approach for generating genotypic data compared with established genomic methods, making it highly scalable and particularly suitable for large‐scale genetic monitoring projects.
Sebastian Sonnenberg   +8 more
wiley   +1 more source

Hepatitis B Virus Infection Status in Japanese Children Prior to Universal Vaccination: Sustained Effectiveness of Mother‐to‐Child Transmission Prevention and Residual Infection Burden

open access: yesHepatology Research, Volume 56, Issue 10, Page 1457-1465, October 2026.
ABSTRACT Aim To evaluate the effectiveness of prevention of mother‐to‐child transmission (PMTCT) over 25 years, we conducted a nationwide epidemiological survey through a comprehensive assessment of hepatitis B virus (HBV) markers. Methods Two cohorts were recruited before universal vaccination: children aged 9–10 years undergoing school health ...
Aiko Sakai   +21 more
wiley   +1 more source

A note on corporate taxation, limited liability, and asymmetric information [PDF]

open access: yes, 2007
corporate taxation, limited liability, H21, H25,
Miglo, A.   +4 more
core   +1 more source

R&D tax credits, innovative activity and the targeting approach

open access: yesEconomics and Business Review
The aim of this study is to investigate whether the French R&D tax credit targeted at small and medium-sized enterprises (SMEs) has a positive impact on innovative activity. The French institutional setting provides a unique research framework as the R&D
Gjymshana Erik   +2 more
doaj   +1 more source

Peripheral Inflammation and Sleep Loss Induce Coordinated Motivational Changes: An Experimental Two‐Hit Stress Model

open access: yesJournal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Sleep loss and low‐grade inflammation are common stressors that affect behaviour and recovery needs. To examine their separate and combined effects on motivation for everyday behaviours, we developed a two‐hit experimental model. Participants (N = 56, 31 women) completed three experimental visits: sleep saturation (two nights, 9 h in bed/night)
John Axelsson   +6 more
wiley   +1 more source

Liquidity Constraints and Tax Liability Targeting of Banks in Ghana: Analysis of Persistence and Distance to Target

open access: yesFoundations of Management
This paper examines the effect of liquidity constraints on tax liability targeting among banks in Ghana, with emphasis on the persistence and speed of adjustment toward tax targets.
BOATENG Kwakye   +2 more
doaj   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang   +13 more
wiley   +1 more source

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