Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT We report a patient with a pathogenic germline variant (PGV) in RB1 and somatic mosaicism for a pathogenic TP53 variant who developed three distinct types of childhood cancer: retinoblastoma, osteosarcoma, and myelodysplastic syndrome (MDS) before the age of 6 years.
Ole Haubjerg Nielsen +8 more
wiley +1 more source
Decontaminating Beef for Escherichia coliO157:H7
Journal of Food Protection, 1998 Beef lean, fat, and connective tissues were inoculated with Escherichia coli O157:H7 before and after a prewashing procedure to compare the efficacy of prewashing and no prewashing on bacterial adherence and, consequently, on the removal of bacteria from the inoculated surfaces. Prewashing consisted of spraying tissues with tap water before inoculation.
I, Delazari +4 more
openaire +2 more sources
An investigation of the expression and adhesin function of H7 flagella in the interaction of Escherichia coli O157 : H7 with bovine intestinal epithelium [PDF]
Cellular Microbiology, 2009 Enterohaemorrhagic Escherichia coli O157 : H7 is a bacterial pathogen that can cause haemorrhagic colitis and haemolytic uremic syndrome. In the primary reservoir host, cattle, the terminal rectum is the principal site of E. coli O157 colonization.
Mahajan, A +11 more
openaire +5 more sources
Genomic Characterization of β-Glucuronidase–Positive Escherichia coli O157:H7 Producing Stx2a
Emerging Infectious Diseases, 2018 Among Shiga toxin (Stx)–producing Escherichia coli (STEC) O157:H7 strains, those producing Stx2a cause more severe diseases. Atypical STEC O157:H7 strains showing a β-glucuronidase–positive phenotype (GP STEC O157:H7) have rarely been isolated from ...
Yoshitoshi Ogura +9 more
doaj +1 more source
Advanced Physics Research, EarlyView.This study explores the use of single‐walled carbon nanotubes (SWCNTs) for thermoelectric (TE) applications to convert waste heat into electricity. By examining two SWCNT types with varying purity, structure, and thickness, it assesses how different solvents used in buckypaper fabrication affect their TE properties.
Marén Gültner +6 more
wiley +1 more source
Humans and platyrrhines share a pattern of articular variance
The Anatomical Record, EarlyView.Abstract Previous work has identified a pattern of articular shape variation in modern human limb joints, in which convex joint surfaces exhibit constrained variance relative to their more variable concave conarticulars. This pattern is notable given that joint morphogenesis is influenced by local biomechanical environments, which vary substantially ...
Haley Horbaly, Liam Zachary
wiley +1 more source
Cattle intestinal microbiota shifts following Escherichia coli O157:H7 vaccination and colonization
PLoS ONE, 2019 Vaccination-induced Escherichia coli O157:H7-specific immune responses have been shown to reduce E. coli O157:H7 shedding in cattle. Although E. coli O157:H7 colonization is correlated with perturbations in intestinal microbial diversity, it is not yet ...
Raies A Mir +6 more
doaj +1 more source
Quantitative assessment of sense and antisense transcripts from genes involved in antigenic variation (vsp genes) and encystation (cwp 1 gene) of Giardia lamblia clone GS/M-83-H7. [PDF]
, 2005 Antigenic variation of the intestinal protozoan parasite Giardia lamblia is caused by an exchange of the parasite's variant surface protein (VSP) coat. Many investigations on antigenic variation were performed with G.
Müller, Norbert +7 more
core +2 more sources
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Past, Present, and Possible Future Human Infection with Influenza Virus A Subtype H7
Emerging Infectious Diseases, 2009 Influenza A subtype H7 viruses have resulted in >100 cases of human infection since 2002 in the Netherlands, Italy, Canada, the United States, and the United Kingdom.
Jessica A. Belser +3 more
doaj +1 more source