Results 171 to 180 of about 3,267 (182)

MPEC 2026-H71 : 2026 HX1

The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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MPEC 2024-H71 : 2024 HK1

The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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MPEC 2025-H71 : 2025 HB1

The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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FLT3-ITD+ AML Blast, Progenitor and Stem Cell Populations Demonstrate Higher Sensitivity to the Hsp90 Inhibitor PU-H71,

Blood, 2011
Abstract Abstract 3500 Hsp90, one of the best-characterized molecular chaperones, plays indispensable roles in folding and assembly, intracellular transport, stabilization, and degradation of proteins, and therefore, facilitating cell signaling.
Hongliang Zong, Tony Taldone, James H. Ahn, Sarah Brennan, Jeanne P. De Leon, Michael W. Becker, Gail J. Roboz, Gabriela Chiosis, Monica L. Guzman   +8 more
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Abstract 2752: Novel inhibitor of HSP90- PU-H71 exhibits significant activity in Ewing sarcoma pre-clinical models.

Cancer Research, 2013
Abstract Ewing sarcoma is characterized by multiple deregulated pathways that mediate cell survival and proliferation. Heat shock protein-90 (HSP90) is a critical component of the multi-chaperone complexes that regulate the disposition and activity of a large number of proteins responsible for the assembly and regulation of cell ...
Srikanth R. Ambati, Eloisi Caldas Lopes, Ullas Mony, Kohji Kosugi, Andre Moreira, Paul Meyers, Gabriela Chiosis, Malcolm Moore   +7 more
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Impact of Epichaperome Inhibitor PU-H71 on Anti-Tumor T Cell Responses and Its Implications for Immune and Cellular Therapy

Blood, 2022
Jeremie Martinet, Mayumi Sugita, Mohammad Alhomoud, Catalina Abad, Gabriela Chiosis, Gail J. Roboz, Olivier Boyer, Monica L. Guzman   +7 more
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Assess the Safety, Tolerability Oral PU-H71 in Subjects Taking Ruxolitinib

Case Medical Research, 2019
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Pre-clinical efficacy of PU-H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma

Molecular Oncology, 2014
Ahmet Zehir, Paul Meyers, Gabriela Chiosis   +2 more
exaly  

A facile and efficient synthesis of d6-labeled PU-H71, a purine-scaffold Hsp90 inhibitor

Journal of Labelled Compounds and Radiopharmaceuticals, 2010
Gabriela Chiosis, Tony Taldone, Danuta Zatorska   +2 more
exaly  

The Preparation and Properties of Ammonia-Triborane, H3NB3H71

Journal of the American Chemical Society, 1959
R W Parry
exaly