Results 31 to 40 of about 1,663 (106)

Metabolic Recoding of NSUN2‐Mediated m5C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m5C‐ENO1 Positive Feedback Loop

Advanced Science, Volume 11, Issue 28, July 24, 2024.
The RNA modification, 5‐methylcytosine (m5C), has recently gained prominence in regulating gene expression and tumorigenesis. This study identifies NSUN2 and YBX1 as the m5C “writer” and “reader” of ENO1 in colorectal cancer, culminating in a positive feedback loop involving the NSUN2/YBX1/m5C‐ENO1 signaling axis, thereby bridging the connection ...
Baoxiang Chen, Yanrong Deng, Yuntian Hong, Lifang Fan, Xiang Zhai, Heng Hu, Siyuan Yin, Quanjiao Chen, Xiaoyu Xie, Xianghai Ren, Jianhong Zhao, Congqing Jiang   +11 more
wiley   +1 more source

KMT2D‐mediated H3K4me1 recruits YBX1 to facilitate triple‐negative breast cancer progression through epigenetic activation of c‐Myc

Clinical and Translational Medicine, Volume 14, Issue 7, July 2024.
YBX1 is a “reader” of KMT2D‐mediated H3K4me1 mark. YBX1 and KMT2D activate the expression of SENP1 and c‐Myc. YBX1 is recruited by H3K4me1 mark to facilitate breast cancer progression. Abstract Background Lysine methyltransferase 2D (KMT2D) mediates mono‐methylation of histone H3 lysine 4 (H3K4me1) in mammals.
Bing Yao, Mengying Xing, Xiangwei Zeng, Ming Zhang, Que Zheng, Zhi Wang, Bo Peng, Shuang Qu, Lingyun Li, Yucui Jin, Haitao Li, Hongyan Yuan, Quan Zhao, Changyan Ma   +13 more
wiley   +1 more source

Hawaiian Volcanic Ash, an Airborne Fomite for Nontuberculous Mycobacteria

GeoHealth, Volume 8, Issue 1, January 2024.
Abstract Nontuberculous mycobacteria (NTM) are environmentally acquired opportunistic pathogens that can cause chronic lung disease. Within the U.S., Hawai'i shows the highest prevalence rates of NTM lung infections. Here, we investigated a potential role for active volcanism at the Kīlauea Volcano located on Hawai'i Island in promoting NTM growth and ...
Stephanie N. Dawrs, Ravleen Virdi, Grant J. Norton, Tamar Elias, Nabeeh A. Hasan, Schuyler Robinson, Jobel Matriz, L. Elaine Epperson, Cody M. Glickman, Sean Beagle, James L. Crooks, Stephen T. Nelson, Edward D. Chan, David E. Damby, Michael Strong, Jennifer R. Honda   +15 more
wiley   +1 more source

Crystal Structures Reveal Hidden Domain Mechanics in Protein Kinase A (PKA). [PDF]

Biology (Basel), 2023
Welsh CL, Conklin AE, Madan LK.
europepmc   +1 more source

The mechanism of mammalian proton-coupled peptide transporters. [PDF]

Elife
Lichtinger SM, Parker JL, Newstead S, Biggin PC.   +3 more
europepmc   +2 more sources

Dynamic regulation of Zn(II) sequestration by calgranulin C. [PDF]

Protein Sci, 2022
Wang Q, Kuci D, Bhattacharya S, Hadden-Perilla JA, Gupta R.   +4 more
europepmc   +1 more source

Exploring Biosurfactant Production from Halophilic Bacteria, Isolated from Burgas Salterns in Bulgaria. [PDF]

Mar Drugs
Berberov K, Boyadzhieva I, Yakimova B, Petkova H, Stoineva I, Nacheva L, Kabaivanova L.   +6 more
europepmc   +1 more source

Multi-Physics Simulation of Tar-Rich Coal In Situ Pyrolysis with a Multiregion Homogenization Treatment. [PDF]

ACS Omega, 2023
Ye Q, Li M, Hao J, Huang Z, Wei J.
europepmc   +1 more source

Determination of the structure and dynamics of linear polypeptide gramicidin A at atomic-scale resolution. [PDF]

RSC Adv
Laxmi Pradhan B, Sen P, Kumar A, Bhunia A, Kishor Dey K, Ghosh M.   +5 more
europepmc   +1 more source

Molecular Principles of Proton-Coupled Quinone Reduction in the Membrane-Bound Superoxide Oxidase. [PDF]

J Am Chem Soc
Riepl D, Abou-Hamdan A, Gellner J, Biner O, Sjöstrand D, Högbom M, von Ballmoos C, Kaila VRI.   +7 more
europepmc   +1 more source