Results 51 to 60 of about 5,681 (173)

Discovery of a Novel Non‐Nucleoside Inhibitor of RNA‐Dependent RNA Polymerase Against Dengue Virus

MedComm, Volume 6, Issue 12, December 2025.
PN‐1, a novel non‐nucleoside inhibitor of the dengue virus RNA‐dependent RNA polymerase (RdRp), was identified from Panax notoginseng. This compound selectively targets the DENV‐2 NS5 RdRp, inducing conformational changes that inhibit enzymatic activity, thereby suppressing DENV replication both in vitro and in vivo.
Xue‐Mei He, Li‐Fang Zou, Jing‐Tao Yu, Tang‐Jia Yang, Zi‐Bin Lu, Hui‐Hui Cao, Wen Li, Bing Chen, Wei Zhao, Jian‐Ping Zuo, Lin‐Zhong Yu, Jun‐Shan Liu   +11 more
wiley   +1 more source

Inheritance and enzymatic basis of anthocyanin malonylation in Fragaria × ananassa

The Plant Journal, Volume 124, Issue 2, October 2025.
Significance Statement Fruits from various cultivars of the cultivated strawberry (Fragaria × ananassa) exhibit significant variation in the levels of malonylated anthocyanins, which is attributed to the differential expression of malonyltransferase genes, whose products demonstrate acceptor substrate promiscuity.
Xiran Wang, Johanna Trinkl, Martha Wulanjati, Annika Haugeneder, Klaus Olbricht, Sonia Osorio, Iraida Amaya, José F. Sánchez‐Sevilla, Béatrice Denoyes, Aurélie Petit, Philippe Chartier, Luca Mazzoni, Bruno Mezzetti, Agnieszka Masny, Björn Usadel, Freya Ziegler, Zhen Yu, Xiaotong Zhu, Wenhao Shi, Chan Li, Chiye Yuan, Huiyun Hu, Timothy D. Hoffmann, Thomas Hoffmann, Wilfried G. Schwab   +24 more
wiley   +1 more source

Identification of the sirohaem biosynthesis pathway in Staphylococcus aureus

The FEBS Journal, 2020
Sirohaem is a modified tetrapyrrole and a key prosthetic group of several enzymes involved in nitrogen and sulfur metabolisms. This work shows that Staphylococcus aureus produces sirohaem through a pathway formed by three independent enzymes.
M. Videira, Susana A. L. Lobo, Filipa L. Sousa, L. M. Saraiva   +3 more
semanticscholar   +1 more source

Complex population genetic structure of the bark beetle predator Thanasimus formicarius (L.) (Coleoptera: Cleridae) across its European range

Agricultural and Forest Entomology, Volume 27, Issue 3, Page 437-451, August 2025.
Abstract Thanasimus formicarius (L.) (Coleoptera: Cleridae) is an important bark beetle predator and can reduce bark beetle population densities of some of the most severe forest pests in Europe. We analysed the population genetics and phylogeography of T.
Eva Papek, Amina Derlić, Markus Melin, Alain Roques, Dragos Cocos, Martin L. Schroeder, Milan Pernek, Dimitrios N. Avtzis, Paulius Zolubas, David T. Williams, Juan A. Pajares, Oğuzhan Sarikaya, Roman Pavlin, Sevdalin Belilov, Martin M. Gossner, M. Lukas Seehausen, Anna Wierzbicka, Lara Kundtner, Christian Stauffer, Martin Schebeck   +19 more
wiley   +1 more source

SUSY Higgs bosons and beyond [PDF]

, 2010
We consider extensions of the Minimal Supersymmetric Standard Model (MSSM) where the extra degrees of freedom interact weakly with the Higgs sector. These models allow to relax the tension between the lower bound on the lightest CP even Higgs mass from ...
Carena, Marcela, Pontón, Eduardo, Zurita, José   +2 more
core  

Simple Non Linear Klein-Gordon Equations in 2 space dimensions, with long range scattering

, 2007
We establish that solutions, to the most simple NLKG equations in 2 space dimensions with mass resonance, exhibits long range scattering phenomena. Modified wave operators and solutions are constructed for these equations.
E. Taflin, Erik Taflin, H. Lindblad, H. Lindblad, J. Ginibre, J.C.H. Simon, J.C.H. Simon, J.M. Delort, L. Hörmander, M. Flato, M. Flato, T. Ozawa   +11 more
core   +1 more source

Tradable Refugee-admission Quotas (TRAQs), the Syrian Crisis and the new European Agenda on Migration

Social Science Research Network, 2015
The Syrian Civil War gave rise to the largest refugee flight reaching Europe since the Yugoslavian wars in the 1990s. The crisis evidenced the deficiencies of the European Union Asylum Policy, which struggled both to offer solutions to Syrian refugees ...
Jesús Fernández-Huertas Moraga, Hillel Rapoport   +1 more
semanticscholar   +1 more source

Modelling and analysis of transformers considering ultra‐wide band frequency‐dependent parameters for high altitude electromagnetic pulse

High Voltage, Volume 10, Issue 2, Page 374-384, April 2025.
Abstract Transformers are widely distributed and extremely important energy conversion equipment in the power system. However, the high altitude electromagnetic pulse (HEMP) can induce a steep pulse voltage with a peak value of up to thousands of kilovolts on the overhead line, and the frequency is up to 100 MHz, which is easy to damage the transformer
Han Wu, Nan Zhang, Jinhua Du, Junna Li, Shuai Dong, Zitao Lv   +5 more
wiley   +1 more source

Higher Genetic Diversity Across Several Small Patches Compared to a Single Large Patch: A Within‐Species Test of SLOSS [PDF]

Evol Appl
ABSTRACT The SLOSS (Single Large or Several Small) debate is crucial in reserve design, focusing on evaluating the conservation efficacy of a single large reserve versus multiple small reserves for species preservation. While accumulating evidence suggests that multiple small reserves may conserve greater species diversity, the question of how to ...
Lei F, Li D, Zhu H, Xia Y, Chen X, Yu J, Guo S, Yu J.   +7 more
europepmc   +2 more sources

Convex Hull of Arithmetic Automata

, 2008
Arithmetic automata recognize infinite words of digits denoting decompositions of real and integer vectors. These automata are known expressive and efficient enough to represent the whole set of solutions of complex linear constraints combining both ...
A. Finkel, A. Schrijver, B. Becker, B. Boigelot, B. Boigelot, B. Boigelot, D. Lugiez, J. Leroux, J. Leroux, J. Leroux, J. Leroux, L. Latour, M. Karr, S. Bardin   +13 more
core   +5 more sources