Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Publ. Astron. Soc. Aust., 2002, 19, 1--5 Molecular Hydrogen in the Lagoon:
The 2.12 mv= 1--0 S(1) line of molecular hydrogen has been imaged in the Hourglass region of M8. The line is emitted from a roughly bipolar region, centred around the O7 star Herschel 36.
Michael G. Burton, Line Emission From
core
Phase-dependent Magnetic Coherence in the Turbulent Interstellar Medium
Magnetic fields permeate the multiphase interstellar medium (ISM), yet their phase-dependent structure remains poorly constrained by observations. Dust polarization and H i emission together offer complementary probes of the plane-of-sky magnetic field ...
Iryna S. Butsky +4 more
doaj +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
We follow up emission line galaxies identified through the near-infrared slitless HST/WFC3 WISP survey with VLT/FORS2 optical spectroscopy. Over 4 WISP fields, we targeted 85 of 138 line emission objects at $0.4\lt z\lt 2$ identified in WFC3 spectroscopy.
MA Malkan (9573533) +16 more
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The 21-SPONGE H I Absorption Line Survey. I. The Temperature of Galactic H I
We present 21 cm Spectral Line Observations of Neutral Gas with the VLA (21-SPONGE), a Karl G. Jansky Very Large Array (VLA) large project (~600 hr) for measuring the physical properties of Galactic neutral hydrogen (H I).
Murray, CE (15583598) +6 more
core
Direct Optimal Mapping Image Power Spectrum and its Window Functions
The key to detecting neutral hydrogen during the epoch of reionization (EoR) is to separate the cosmological signal from the dominating foreground radiation.
Zhilei Xu +83 more
doaj +1 more source
The Responsivity of Mg
Abstract This study systematically investigates the responsivity ( α ) of broad emission-line (BEL) variations (Mg ii λ 2798, C iv λ 1549, H
Wei-Rong Huang +4 more
openaire +1 more source
Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello +10 more
wiley +1 more source
The 21 cm forest is a sensitive probe for the early heating process and small-scale structures during the epoch of reionization (EOR), to be realized with the upcoming Square Kilometre Array (SKA). Its detection relies on the availability of radio-bright
Qi Niu +4 more
doaj +1 more source

