Results 131 to 140 of about 90,421 (247)

The \u3cem\u3edapE\u3c/em\u3e-encoded \u3cem\u3eN\u3c/em\u3e-succinyl-l,l-diaminopimelic Acid Desuccinylase from \u3cem\u3eHaemophilus influenzae\u3c/em\u3e Contains Two Active-site Histidine Residues [PDF]

, 2009
The catalytic and structural properties of the H67A and H349A dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE) from Haemophilus influenzae were investigated.
Bennett, Brian, Bienvenue, David L., Gillner, Danuta, Holz, Richard C., Joachimiak, Andzrej, Nocek, Boguslaw P., Zachary, Vincentos   +6 more
core   +1 more source

T3SS effector and regulator discovery by predicting interacting partners of T3SS chaperones in Pseudomonas aeruginosa

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Pseudomonas aeruginosa is a prominent opportunistic pathogen whose virulence is closely linked to its Type III Secretion System (T3SS), a specialized apparatus that injects effector proteins into host cells. T3SS chaperones are essential for stabilizing, delivering, and regulating T3SS expression.
Jing Zhang
wiley   +1 more source

Identification of a Histidine Metal Ligand in the \u3cem\u3eargE\u3c/em\u3e-Encoded \u3cem\u3eN\u3c/em\u3e-Acetyl-L-Ornithine Deacetylase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2013
The H355A, H355K, H80A, and H80K mutant enzymes of the argE-encoded N-acetyl-L-ornithine deacetylase (ArgE) from Escherichia coli were prepared, however, only the H355A enzyme was found to be soluble. Kinetic analysis of the Co(II)-loaded H355A exhibited
Gillner, Danuta, Holz, Richard C., Liu, Dali, McGregor, Wade C., Swierczek, Sabina I.   +4 more
core   +1 more source

The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 5, Page 1092-1103, May 2026.
ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham, Adele K. Williamson, Emily K. Grout, Joanna L. Hicks   +3 more
wiley   +1 more source

Carriage Rate of Nasopharyngeal Haemophilus Influenzae among Children under 6 Years Old in Tehran, Iran

Journal of Medical Microbiology and Infectious Diseases, 2014
Introduction : Haemophilus influenzae is a gram-negative bacterium causing a variety of respiratory infections in developing countries, especially in children. Nasopharynx carriers of H.
Pantea Jalali, Seyed Fazlollah Mousavi, Nima Rezaei   +2 more
doaj  

AI‐Enabled Imaging for Pathogen Detection Under Stress Conditions: A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Advances in pathogen detection that incorporate artificial intelligence (AI) may capture microbial signals under challenging environmental conditions that traditional methods miss. This systematic review evaluates the application, performance, and methodological characteristics of AI‐enabled imaging for pathogen detection, including its impact
MeiLi Papa, Gillian Kuehnle, Yoo Jung (Erika) Oh, Jiyoon Yi   +3 more
wiley   +1 more source

Treosulfan–fludarabine conditioning in infants with severe combined immunodeficiencies: Extended study of the UK paediatric treosulfan study

British Journal of Haematology, Volume 208, Issue 5, Page 1713-1723, May 2026.
Summary Allogeneic haematopoietic stem cell transplantation (HSCT) is a curative therapy for severe combined immunodeficiency (SCID). Conditioning improves donor engraftment and freedom from immunoglobulin replacement (IgR) but increases the risks of acute and late toxicity. Treosulfan, a reduced toxicity alkylating agent, has emerged as an alternative
Su Han Lum, Sinéad Greener, Irum Latif Memon, Persis Amrolia, Zohreh Nademi, Robert Chiesa, Juliana Silva, Helen Young, Stephen Owens, Eleri Williams, Khuen Foong Ng, Terry Flood, Andrew R Gennery, Sophie Hambleton, Kanchan Rao, Mary Slatter   +15 more
wiley   +1 more source

Prevalence and Nationality Distribution of Known and Novel Genetic Variants in Children With Primary Ciliary Dyskinesia in the State of Qatar

Clinical Genetics, Volume 109, Issue 5, Page 937-945, May 2026.
CT scan image of a 17‐year‐old female with primary ciliary dyskinesia (PCD) showing dextrocardia and bilateral bronchiectasis. The study describes genetic mutations affecting patients with PCD in Qatar and the corresponding clinical phenotype of affected patients.
Atqah AbdulWahab, Reem Mohamed, Amani Hamid, Hadeel Alzoubi, Donald R. Love, Kelly Robinson, Ibrahim Janahi, Mutasim Abu‐Hasan   +7 more
wiley   +1 more source

Nature of {varphi}X174 Linear DNA from a DNA Ligase-Defective Host [PDF]

, 1974
Linear DNAs have been prepared from {varphi}X phage and from {varphi}X RF II (double-stranded circular form of {varphi}X DNA, formed during infection and nicked in one or both strands) molecules derived from infection at the restrictive temperature of ...
Miller, Lois K., Sinsheimer, Robert L.
core  

Epidemiological Characteristics and Co‐Detection Patterns of Rhinovirus (A/B/C) and Influenza A Virus in a Regional Respiratory Cohort in Hunan, China

The Clinical Respiratory Journal, Volume 20, Issue 5, May 2026.
This study analyzed 386 rhinovirus infections (dominant Type A, 60.9%; high 73.1% coinfection rate) and Influenza A interactions. Rhinovirus A/B showed mutual exclusivity with Influenza A, while Type C had near‐random association, with temporal prevalence fluctuations observed. ABSTRACT Objective To characterize the epidemiological profile, coinfection
Feicheng Yang, Ping Bai, Jiaxuan Zhang, Juqi Peng, Qing Hu, Yanchun Li   +5 more
wiley   +1 more source