Results 41 to 50 of about 90,421 (247)

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga   +20 more
wiley   +1 more source

Lower airway colonization and inflammatory response in COPD: a focus on Haemophilus influenzae [PDF]

open access: yes, 2014
Bacterial infection of the lower respiratory tract in chronic obstructive pulmonary disease (COPD) patients is common both in stable patients and during acute exacerbations.
Finney, LJ   +4 more
core   +2 more sources

Functionalizing Conductive Diamond: Recent Advance in Fabrication, Modifications, and Applications

open access: yesCarbon Energy, EarlyView.
This review highlights recent advancements in the synthesis, modification, and electrochemical applications of conductive diamond, particularly boron‐doped diamond (BDD). It emphasizes progress in fabrication methods, including CVD and HPHT, and explores modifications such as doping, surface terminations, and composite design, enabling significant ...
Ning Linghu, Xin Jiang, Jing Xu
wiley   +1 more source

Comprehensive spatial profiling reveals transitional microbiome dynamics and microbial heterogeneity in pediatric adenoid hypertrophy

open access: yesiMetaOmics, EarlyView.
This study characterizes the upper respiratory microbiome in 276 children (101 Adenoid hypertrophy (AH) 119 Adenotonsillar hypertrophy (ATH), 11 Tonsil hypertrophy (TH), and 45 healthy controls by analyzing 1149 samples across five distinct niches: nasopharyngeal swabs (NS), adenoid swab (AS), and tonsil swabs (TS), plus adenoid tissues (AT) and tonsil
Kaining Chen   +28 more
wiley   +1 more source

Differential responses of COPD macrophages to respiratory bacterial pathogens

open access: yesERJ Open Research, 2022
COPD patients have increased susceptibility to airway bacterial colonisation. Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae are three of the most common respiratory bacterial species in COPD. H.
Simon Lea   +7 more
doaj   +1 more source

Recent lateral gene transfer from Pasteurella multocida into Haemophilus influenzae [PDF]

open access: yes, 2005
only availableHaemophilus influenzae is a gram-negative bacterium that exclusively colonizes humans. Nonencapsulated strains of the bacterium are found in the upper respiratory tract of healthy humans, but can also cause the respiratory diseases otitis ...
Bratkowski, Matthew   +2 more
core  

Structural studies on lipopolysaccharides from haemophilus species [PDF]

open access: yes, 2011
Background: Carbohydrates are indispensable mediators for a variety of cellular interactions. In biological systems carbohydrates are usually linked to a carrier as e.g. proteins or lipids. One example is the molecule lipopolysaccharide (LPS).
Twelkmeyer, Brigitte
core   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma   +6 more
wiley   +1 more source

Risk Factors for Otitis Media and Carriage of Multiple Strains of Haemophilus influenzae and Streptococcus pneumoniae

open access: yesEmerging Infectious Diseases, 2000
We studied genetic diversity in Streptococcus pneumoniae and Haemophilus influenzae in throat culture isolates from 38 children attending two day-care centers in Michigan. Culture specimens were collected weekly; 184 S. pneumoniae and 418 H.
Jennifer St. Sauver   +5 more
doaj   +1 more source

Oldenlandia diffusa Extract Inhibits Biofilm Formation by Haemophilus influenzae Clinical Isolates. [PDF]

open access: yesPLoS ONE, 2016
Oldenlandia diffusa has been empirically used as a therapeutic adjunct for the treatment of respiratory infections. To establish the basic evidence of its clinical usefulness, antimicrobial and biofilm inhibitory activities of an O.
Takeaki Wajima   +4 more
doaj   +1 more source

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